Triazaverin Prophylactic Efficacy Against Influenza Virus A (H5N1)
The experimental study of the prophylactic efficacy of Triazaverin against the experimental form of the influenza virus A (H5N1) on albino mice intranasally infected with the influenza virus A/Chicken/Kurgan/Russia/02/05 vs. the reference drugs Tamiflu®, Remantadin and Arbidol® showed that in doses...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
| Subjects: | |
| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/330 |
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| _version_ | 1849389244888383488 |
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| author | S. YA. Loginova S. V. Borisevich B. A. Maksimov V. P. Bondarev S. K. Kotovskaya V. L. Rusinov V. N. Charushin O. N. Chupakhin |
| author_facet | S. YA. Loginova S. V. Borisevich B. A. Maksimov V. P. Bondarev S. K. Kotovskaya V. L. Rusinov V. N. Charushin O. N. Chupakhin |
| author_sort | S. YA. Loginova |
| collection | DOAJ |
| description | The experimental study of the prophylactic efficacy of Triazaverin against the experimental form of the influenza virus A (H5N1) on albino mice intranasally infected with the influenza virus A/Chicken/Kurgan/Russia/02/05 vs. the reference drugs Tamiflu®, Remantadin and Arbidol® showed that in doses of 1 to 100 mg/kg it was efficient in the animal protection from death. The drug was also efficient in the urgent prophylaxis. Triazaverin effectively inhibited the influenza A virus multiplication in the lungs of the albino mice. |
| format | Article |
| id | doaj-art-2f9d299f484345cb9353cf64de3cf8d0 |
| institution | Kabale University |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-2f9d299f484345cb9353cf64de3cf8d02025-08-20T03:42:01ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01559-102528329Triazaverin Prophylactic Efficacy Against Influenza Virus A (H5N1)S. YA. Loginova0S. V. Borisevich1B. A. Maksimov2V. P. Bondarev3S. K. Kotovskaya4V. L. Rusinov5V. N. Charushin6O. N. Chupakhin7Virological Centre, Central Research Institute No 48, Ministry of Defense of the Russian Federation, Sergiev PosadVirological Centre, Central Research Institute No 48, Ministry of Defense of the Russian Federation, Sergiev PosadVirological Centre, Central Research Institute No 48, Ministry of Defense of the Russian Federation, Sergiev PosadVirological Centre, Central Research Institute No 48, Ministry of Defense of the Russian Federation, Sergiev PosadB. N.Yeltsin Urals State Technical University, EkaterinburgB. N.Yeltsin Urals State Technical University, EkaterinburgB. N.Yeltsin Urals State Technical University, EkaterinburgB. N.Yeltsin Urals State Technical University, EkaterinburgThe experimental study of the prophylactic efficacy of Triazaverin against the experimental form of the influenza virus A (H5N1) on albino mice intranasally infected with the influenza virus A/Chicken/Kurgan/Russia/02/05 vs. the reference drugs Tamiflu®, Remantadin and Arbidol® showed that in doses of 1 to 100 mg/kg it was efficient in the animal protection from death. The drug was also efficient in the urgent prophylaxis. Triazaverin effectively inhibited the influenza A virus multiplication in the lungs of the albino mice.https://www.antibiotics-chemotherapy.ru/jour/article/view/330influenza virus atriazaverinantiviral efficacyprophylaxis |
| spellingShingle | S. YA. Loginova S. V. Borisevich B. A. Maksimov V. P. Bondarev S. K. Kotovskaya V. L. Rusinov V. N. Charushin O. N. Chupakhin Triazaverin Prophylactic Efficacy Against Influenza Virus A (H5N1) Антибиотики и Химиотерапия influenza virus a triazaverin antiviral efficacy prophylaxis |
| title | Triazaverin Prophylactic Efficacy Against Influenza Virus A (H5N1) |
| title_full | Triazaverin Prophylactic Efficacy Against Influenza Virus A (H5N1) |
| title_fullStr | Triazaverin Prophylactic Efficacy Against Influenza Virus A (H5N1) |
| title_full_unstemmed | Triazaverin Prophylactic Efficacy Against Influenza Virus A (H5N1) |
| title_short | Triazaverin Prophylactic Efficacy Against Influenza Virus A (H5N1) |
| title_sort | triazaverin prophylactic efficacy against influenza virus a h5n1 |
| topic | influenza virus a triazaverin antiviral efficacy prophylaxis |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/330 |
| work_keys_str_mv | AT syaloginova triazaverinprophylacticefficacyagainstinfluenzavirusah5n1 AT svborisevich triazaverinprophylacticefficacyagainstinfluenzavirusah5n1 AT bamaksimov triazaverinprophylacticefficacyagainstinfluenzavirusah5n1 AT vpbondarev triazaverinprophylacticefficacyagainstinfluenzavirusah5n1 AT skkotovskaya triazaverinprophylacticefficacyagainstinfluenzavirusah5n1 AT vlrusinov triazaverinprophylacticefficacyagainstinfluenzavirusah5n1 AT vncharushin triazaverinprophylacticefficacyagainstinfluenzavirusah5n1 AT onchupakhin triazaverinprophylacticefficacyagainstinfluenzavirusah5n1 |