Stable developmental patterns of gene expression without morphogen gradients.

Gene expression patterns in developing organisms are established by groups of cross-regulating target genes that are driven by morphogen gradients. As development progresses, morphogen activity is reduced, leaving the emergent pattern without stabilizing positional cues and at risk of rapid deterior...

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Bibliographic Details
Main Authors: Maciej Majka, Nils B Becker, Pieter Rein Ten Wolde, Marcin Zagorski, Thomas R Sokolowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012555
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