Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in rats
Purpose: This study aims to investigate whether contrast-enhanced ultrasound (CEUS) could be used to reveal the status of blood supply of the superficial flap of rat model in the early postoperative stage. Methods: One viable and one ischemic random-pattern flap were prepared on the left and righ...
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| Format: | Article |
| Language: | English |
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Medical Journals Sweden
2024-09-01
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| Series: | Journal of Plastic Surgery and Hand Surgery |
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| Online Access: | https://medicaljournalssweden.se/JPHS/article/view/39975 |
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| _version_ | 1849224349583671296 |
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| author | Jian-Xun Ma You-Chen Xia Zhi-Yong Bai Hua-Bin Zhang Xia Xie |
| author_facet | Jian-Xun Ma You-Chen Xia Zhi-Yong Bai Hua-Bin Zhang Xia Xie |
| author_sort | Jian-Xun Ma |
| collection | DOAJ |
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Purpose: This study aims to investigate whether contrast-enhanced ultrasound (CEUS) could be used to reveal the status of blood supply of the superficial flap of rat model in the early postoperative stage.
Methods: One viable and one ischemic random-pattern flap were prepared on the left and right back of the same rat respectively with a number of 40. CEUS examinations were applied within 12 h and 7 days postoperatively, and the quantitative measurements of microvascular blood volume (BV) of the base and the end of both flaps were expressed using acoustic intensity as a ratio to that of the healthy skin.
Results: Within 12 h post operation, there was a smaller BV value of the ischemic ends than that of both the ischemic bases and viable ends (p < 0.001), while no difference was indicated between ischemic bases and viable bases or between viable bases and viable ends. The same result was provided 7 days post operation.
Conclusion: Microcirculation of superficial tissues such as random-pattern flaps in this rat model can be assessed quantitatively by CEUS. It could sensitively and accurately reveal the objective status of tissue perfusion in the early postoperative stage.
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| format | Article |
| id | doaj-art-2f92f0b26003416d8c3160d5a66e55ee |
| institution | Kabale University |
| issn | 2000-6764 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Journal of Plastic Surgery and Hand Surgery |
| spelling | doaj-art-2f92f0b26003416d8c3160d5a66e55ee2025-08-25T11:16:42ZengMedical Journals SwedenJournal of Plastic Surgery and Hand Surgery2000-67642024-09-015910.2340/jphs.v59.39975Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in ratsJian-Xun Ma0https://orcid.org/0000-0003-3947-509XYou-Chen Xia1https://orcid.org/0000-0001-5602-1319Zhi-Yong Bai2https://orcid.org/0000-0003-2947-5512Hua-Bin Zhang3https://orcid.org/0009-0003-4353-4627Xia Xie4https://orcid.org/0009-0001-3996-2456Department of Plastic Surgery, Peking University Third Hospital, Beijing, ChinaDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, ChinaDepartment of Ultrasound, Beijing Tsinghua Changgung Hospital, Beijing, ChinaDepartment of Ultrasound, Beijing Tsinghua Changgung Hospital, Beijing, ChinaDepartment of Ultrasound, Beijing Tsinghua Changgung Hospital, Beijing, China Purpose: This study aims to investigate whether contrast-enhanced ultrasound (CEUS) could be used to reveal the status of blood supply of the superficial flap of rat model in the early postoperative stage. Methods: One viable and one ischemic random-pattern flap were prepared on the left and right back of the same rat respectively with a number of 40. CEUS examinations were applied within 12 h and 7 days postoperatively, and the quantitative measurements of microvascular blood volume (BV) of the base and the end of both flaps were expressed using acoustic intensity as a ratio to that of the healthy skin. Results: Within 12 h post operation, there was a smaller BV value of the ischemic ends than that of both the ischemic bases and viable ends (p < 0.001), while no difference was indicated between ischemic bases and viable bases or between viable bases and viable ends. The same result was provided 7 days post operation. Conclusion: Microcirculation of superficial tissues such as random-pattern flaps in this rat model can be assessed quantitatively by CEUS. It could sensitively and accurately reveal the objective status of tissue perfusion in the early postoperative stage. https://medicaljournalssweden.se/JPHS/article/view/39975contrast-enhanced ultrasoundflap transplantationmicrocirculation |
| spellingShingle | Jian-Xun Ma You-Chen Xia Zhi-Yong Bai Hua-Bin Zhang Xia Xie Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in rats Journal of Plastic Surgery and Hand Surgery contrast-enhanced ultrasound flap transplantation microcirculation |
| title | Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in rats |
| title_full | Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in rats |
| title_fullStr | Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in rats |
| title_full_unstemmed | Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in rats |
| title_short | Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in rats |
| title_sort | experimental study of contrast enhanced ultrasound in the evaluation of random pattern flap blood supply in the early postoperative stage in rats |
| topic | contrast-enhanced ultrasound flap transplantation microcirculation |
| url | https://medicaljournalssweden.se/JPHS/article/view/39975 |
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