Chondroblastoma of the femoral head:current and future therapeutic options
Chondroblastoma of the femoral head is a benign tumor originating from immature chondrocytes (chondroblasts), also known as Codman’s tumor. This tumor is mainly located in the epiphysis of the end of long bones, especially in the region of the femoral head. It is more common in children and adolesce...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-08-01
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| Series: | Journal of Bone Oncology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212137425000387 |
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| author | Jun Teng Yitong Ding Can Liu Yangfei Yi Jie Wen Sheng Xiao Xiaohong Jian Yufei Li |
| author_facet | Jun Teng Yitong Ding Can Liu Yangfei Yi Jie Wen Sheng Xiao Xiaohong Jian Yufei Li |
| author_sort | Jun Teng |
| collection | DOAJ |
| description | Chondroblastoma of the femoral head is a benign tumor originating from immature chondrocytes (chondroblasts), also known as Codman’s tumor. This tumor is mainly located in the epiphysis of the end of long bones, especially in the region of the femoral head. It is more common in children and adolescents. Its etiology is derived from embryonic cartilage, or mutations in chondroblasts. The diagnosis mainly depends on imaging examination and histopathological examination. Surgical resection is the main treatment method, and there are also many new methods such as gene therapy and immunotherapy. This article reviews the etiology, diagnosis and treatment of chondroblastoma of the femoral head, so as to provide ideas and basis for further clinical research on adolescent chondroblastoma of the femoral head. |
| format | Article |
| id | doaj-art-2f811d9bc5134fe6aedea59d2c76352e |
| institution | DOAJ |
| issn | 2212-1374 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Bone Oncology |
| spelling | doaj-art-2f811d9bc5134fe6aedea59d2c76352e2025-08-20T02:47:27ZengElsevierJournal of Bone Oncology2212-13742025-08-015310069710.1016/j.jbo.2025.100697Chondroblastoma of the femoral head:current and future therapeutic optionsJun Teng0Yitong Ding1Can Liu2Yangfei Yi3Jie Wen4Sheng Xiao5Xiaohong Jian6Yufei Li7Department of Pediatric Orthopedics, Zhangjiajie People’s Hospital, Zhangjiajie, Hunan, ChinaDepartment of Anatomy, Hunan Normal University School of Medicine, Changsha, Hunan 410005, ChinaDepartment of Anatomy, Hunan Normal University School of Medicine, Changsha, Hunan 410005, ChinaDepartment of Anatomy, Hunan Normal University School of Medicine, Changsha, Hunan 410005, ChinaDepartment of Anatomy, Hunan Normal University School of Medicine, Changsha, Hunan 410005, China; Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410013, China; Corresponding authors at: Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410013, China.Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410013, China; Corresponding authors at: Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410013, China.Department of Anatomy, Hunan Normal University School of Medicine, Changsha, Hunan 410005, ChinaDepartment of Anatomy, Hunan Normal University School of Medicine, Changsha, Hunan 410005, ChinaChondroblastoma of the femoral head is a benign tumor originating from immature chondrocytes (chondroblasts), also known as Codman’s tumor. This tumor is mainly located in the epiphysis of the end of long bones, especially in the region of the femoral head. It is more common in children and adolescents. Its etiology is derived from embryonic cartilage, or mutations in chondroblasts. The diagnosis mainly depends on imaging examination and histopathological examination. Surgical resection is the main treatment method, and there are also many new methods such as gene therapy and immunotherapy. This article reviews the etiology, diagnosis and treatment of chondroblastoma of the femoral head, so as to provide ideas and basis for further clinical research on adolescent chondroblastoma of the femoral head.http://www.sciencedirect.com/science/article/pii/S2212137425000387ChondroblastomaEtiologyDiagnosisTreatmentFemoral head |
| spellingShingle | Jun Teng Yitong Ding Can Liu Yangfei Yi Jie Wen Sheng Xiao Xiaohong Jian Yufei Li Chondroblastoma of the femoral head:current and future therapeutic options Journal of Bone Oncology Chondroblastoma Etiology Diagnosis Treatment Femoral head |
| title | Chondroblastoma of the femoral head:current and future therapeutic options |
| title_full | Chondroblastoma of the femoral head:current and future therapeutic options |
| title_fullStr | Chondroblastoma of the femoral head:current and future therapeutic options |
| title_full_unstemmed | Chondroblastoma of the femoral head:current and future therapeutic options |
| title_short | Chondroblastoma of the femoral head:current and future therapeutic options |
| title_sort | chondroblastoma of the femoral head current and future therapeutic options |
| topic | Chondroblastoma Etiology Diagnosis Treatment Femoral head |
| url | http://www.sciencedirect.com/science/article/pii/S2212137425000387 |
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