Liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomalies

We describe the use and assess the safety of liposomal bupivacaine (LB) infiltration for prolonged postprocedural analgesia after procedures to treat vascular anomalies. This is a single-center prospective study. Consecutive patients aged ≥6 years undergoing painful interventions for vascular anomal...

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Main Authors: Mohammad A. Amarneh, MD, Kyung Kim, MD, Raja Shaikh, MD, Cindy L. Kerr, CPNP, Horacio Padua, MD, Gulraiz Chaudry, MB, ChB, Ahmad I. Alomari, MD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468428725000784
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author Mohammad A. Amarneh, MD
Kyung Kim, MD
Raja Shaikh, MD
Cindy L. Kerr, CPNP
Horacio Padua, MD
Gulraiz Chaudry, MB, ChB
Ahmad I. Alomari, MD
author_facet Mohammad A. Amarneh, MD
Kyung Kim, MD
Raja Shaikh, MD
Cindy L. Kerr, CPNP
Horacio Padua, MD
Gulraiz Chaudry, MB, ChB
Ahmad I. Alomari, MD
author_sort Mohammad A. Amarneh, MD
collection DOAJ
description We describe the use and assess the safety of liposomal bupivacaine (LB) infiltration for prolonged postprocedural analgesia after procedures to treat vascular anomalies. This is a single-center prospective study. Consecutive patients aged ≥6 years undergoing painful interventions for vascular anomalies were included. Data collected included patient demographics, diagnosis, procedure details, LB dosage, periprocedural pain levels, side effects, and the use of additional analgesics. Follow-up extended through postprocedural day 5. LB was used in 26 procedures in 24 patients with mean age of 17.0 years (range, 6.0-33.0 years; median, 17.5 years). One patient was excluded owing to a lack of follow-up. Twenty patients did not require any pain medication in the recovery unit. The mean pain level was 4, 2, 2, and 2 on postoperative days 1, 2, 3, and 5, respectively. No side effects were noted. LB proved to be a safe and likely effective local anesthetic agent, providing prolonged postprocedural analgesia for patients undergoing painful treatments for vascular anomalies.
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spelling doaj-art-2f7e776c4e3e435d88b4e87ad302eb092025-08-20T03:08:33ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872025-08-0111410179610.1016/j.jvscit.2025.101796Liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomaliesMohammad A. Amarneh, MD0Kyung Kim, MD1Raja Shaikh, MD2Cindy L. Kerr, CPNP3Horacio Padua, MD4Gulraiz Chaudry, MB, ChB5Ahmad I. Alomari, MD6Correspondence: Mohammad A. Amarneh, MD, Division of Vascular and Interventional Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115; Division of Vascular and Interventional Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MADivision of Vascular and Interventional Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MADivision of Vascular and Interventional Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MADivision of Vascular and Interventional Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MADivision of Vascular and Interventional Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MADivision of Vascular and Interventional Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MADivision of Vascular and Interventional Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MAWe describe the use and assess the safety of liposomal bupivacaine (LB) infiltration for prolonged postprocedural analgesia after procedures to treat vascular anomalies. This is a single-center prospective study. Consecutive patients aged ≥6 years undergoing painful interventions for vascular anomalies were included. Data collected included patient demographics, diagnosis, procedure details, LB dosage, periprocedural pain levels, side effects, and the use of additional analgesics. Follow-up extended through postprocedural day 5. LB was used in 26 procedures in 24 patients with mean age of 17.0 years (range, 6.0-33.0 years; median, 17.5 years). One patient was excluded owing to a lack of follow-up. Twenty patients did not require any pain medication in the recovery unit. The mean pain level was 4, 2, 2, and 2 on postoperative days 1, 2, 3, and 5, respectively. No side effects were noted. LB proved to be a safe and likely effective local anesthetic agent, providing prolonged postprocedural analgesia for patients undergoing painful treatments for vascular anomalies.http://www.sciencedirect.com/science/article/pii/S2468428725000784Liposomal bupivacaineLocal anesthesiaVascular anomalies
spellingShingle Mohammad A. Amarneh, MD
Kyung Kim, MD
Raja Shaikh, MD
Cindy L. Kerr, CPNP
Horacio Padua, MD
Gulraiz Chaudry, MB, ChB
Ahmad I. Alomari, MD
Liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomalies
Journal of Vascular Surgery Cases and Innovative Techniques
Liposomal bupivacaine
Local anesthesia
Vascular anomalies
title Liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomalies
title_full Liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomalies
title_fullStr Liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomalies
title_full_unstemmed Liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomalies
title_short Liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomalies
title_sort liposomal bupivacaine infiltration for postprocedural analgesia following interventional procedures for vascular anomalies
topic Liposomal bupivacaine
Local anesthesia
Vascular anomalies
url http://www.sciencedirect.com/science/article/pii/S2468428725000784
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