Harnessing Brewery Spent Grain for Polyhydroxyalkanoate Production
The utility of brewery spent grain (BSG), a byproduct of the beer production process, for the synthesis of polyhydroxyalkanoates (PHAs), is a significant advancement towards sustainable and cost-effective biopolymer production. This paper reviews the upcycling potential of BSG as a substrate for PHA...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-06-01
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| Series: | Macromol |
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| Online Access: | https://www.mdpi.com/2673-6209/4/3/26 |
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| author | Robe D. Terfa Priyanshi N. Patel Hwidong D. Kim Matthew D. Gacura Gary Vanderlaan Longyan Chen Xiaoxu Ji Davide Piovesan |
| author_facet | Robe D. Terfa Priyanshi N. Patel Hwidong D. Kim Matthew D. Gacura Gary Vanderlaan Longyan Chen Xiaoxu Ji Davide Piovesan |
| author_sort | Robe D. Terfa |
| collection | DOAJ |
| description | The utility of brewery spent grain (BSG), a byproduct of the beer production process, for the synthesis of polyhydroxyalkanoates (PHAs), is a significant advancement towards sustainable and cost-effective biopolymer production. This paper reviews the upcycling potential of BSG as a substrate for PHA production, utilizing various biotechnological approaches to convert this abundant waste material into high-value biodegradable polymers. Through a comprehensive review of recent studies, we highlight the biochemical composition of BSG and its suitability for microbial fermentation processes. This research delves into different methodologies for PHA production from BSG, including the use of mixed microbial cultures (MMCs) for the synthesis of volatile fatty acids (VFAs), a critical precursor in PHA production, and solid-state fermentation (SSF) techniques. We also examine the optimization of process parameters such as pH, temperature, and microbial concentration through the application of the Doehlert design, revealing the intricate relationships between these factors and their impact on VFA profiles and PHA yields. Additionally, this paper discusses challenges and future perspectives for enhancing the efficiency and economic viability of PHA production from BSG. By harnessing the untapped potential of BSG, this research contributes to the development of a circular economy model, emphasizing waste valorization and the creation of sustainable alternatives to conventional plastics. |
| format | Article |
| id | doaj-art-2f79ed373e3248fd9a2248e5bd625f0c |
| institution | OA Journals |
| issn | 2673-6209 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Macromol |
| spelling | doaj-art-2f79ed373e3248fd9a2248e5bd625f0c2025-08-20T01:55:38ZengMDPI AGMacromol2673-62092024-06-014344846110.3390/macromol4030026Harnessing Brewery Spent Grain for Polyhydroxyalkanoate ProductionRobe D. Terfa0Priyanshi N. Patel1Hwidong D. Kim2Matthew D. Gacura3Gary Vanderlaan4Longyan Chen5Xiaoxu Ji6Davide Piovesan7Department of Biomedical Industrial and Systems Engineering, Gannon University, Erie, PA 16541, USADepartment of Biomedical Industrial and Systems Engineering, Gannon University, Erie, PA 16541, USADepartment of Environmental Science and Engineering, Gannon University, Erie, PA 16541, USADepartment of Biology, Gannon University, Erie, PA 16541, USADepartment of Biology, Gannon University, Erie, PA 16541, USADepartment of Biomedical Industrial and Systems Engineering, Gannon University, Erie, PA 16541, USADepartment of Biomedical Industrial and Systems Engineering, Gannon University, Erie, PA 16541, USADepartment of Biomedical Industrial and Systems Engineering, Gannon University, Erie, PA 16541, USAThe utility of brewery spent grain (BSG), a byproduct of the beer production process, for the synthesis of polyhydroxyalkanoates (PHAs), is a significant advancement towards sustainable and cost-effective biopolymer production. This paper reviews the upcycling potential of BSG as a substrate for PHA production, utilizing various biotechnological approaches to convert this abundant waste material into high-value biodegradable polymers. Through a comprehensive review of recent studies, we highlight the biochemical composition of BSG and its suitability for microbial fermentation processes. This research delves into different methodologies for PHA production from BSG, including the use of mixed microbial cultures (MMCs) for the synthesis of volatile fatty acids (VFAs), a critical precursor in PHA production, and solid-state fermentation (SSF) techniques. We also examine the optimization of process parameters such as pH, temperature, and microbial concentration through the application of the Doehlert design, revealing the intricate relationships between these factors and their impact on VFA profiles and PHA yields. Additionally, this paper discusses challenges and future perspectives for enhancing the efficiency and economic viability of PHA production from BSG. By harnessing the untapped potential of BSG, this research contributes to the development of a circular economy model, emphasizing waste valorization and the creation of sustainable alternatives to conventional plastics.https://www.mdpi.com/2673-6209/4/3/26solid-state fermentationmixed microbial culturevolatile fatty acidsolid-state enzymatic hydrolysis |
| spellingShingle | Robe D. Terfa Priyanshi N. Patel Hwidong D. Kim Matthew D. Gacura Gary Vanderlaan Longyan Chen Xiaoxu Ji Davide Piovesan Harnessing Brewery Spent Grain for Polyhydroxyalkanoate Production Macromol solid-state fermentation mixed microbial culture volatile fatty acid solid-state enzymatic hydrolysis |
| title | Harnessing Brewery Spent Grain for Polyhydroxyalkanoate Production |
| title_full | Harnessing Brewery Spent Grain for Polyhydroxyalkanoate Production |
| title_fullStr | Harnessing Brewery Spent Grain for Polyhydroxyalkanoate Production |
| title_full_unstemmed | Harnessing Brewery Spent Grain for Polyhydroxyalkanoate Production |
| title_short | Harnessing Brewery Spent Grain for Polyhydroxyalkanoate Production |
| title_sort | harnessing brewery spent grain for polyhydroxyalkanoate production |
| topic | solid-state fermentation mixed microbial culture volatile fatty acid solid-state enzymatic hydrolysis |
| url | https://www.mdpi.com/2673-6209/4/3/26 |
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