Study protocol for a randomized controlled effectiveness trial of THRIVE group and peer coaching to promote suicide recovery in crisis stabilization centers

Crisis Stabilization Centers (CSCs) offer a person-centered, community-based alternative to Emergency Departments for suicide prevention. CSCs may facilitate the expansion of the 988 Suicide Prevention Lifeline by providing callers with places to go in communities to receive treatment. However, new,...

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Main Authors: Jennifer D. Lockman, Anthony R. Pisani, M. Alexis Kirk, Kimberly A. Van Orden, Ian J. Cero, Margaret E. Balfour, Kristina Mossgraber, David Jacobowitz, Kenneth R. Conner
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Contemporary Clinical Trials Communications
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Online Access:http://www.sciencedirect.com/science/article/pii/S2451865425000857
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author Jennifer D. Lockman
Anthony R. Pisani
M. Alexis Kirk
Kimberly A. Van Orden
Ian J. Cero
Margaret E. Balfour
Kristina Mossgraber
David Jacobowitz
Kenneth R. Conner
author_facet Jennifer D. Lockman
Anthony R. Pisani
M. Alexis Kirk
Kimberly A. Van Orden
Ian J. Cero
Margaret E. Balfour
Kristina Mossgraber
David Jacobowitz
Kenneth R. Conner
author_sort Jennifer D. Lockman
collection DOAJ
description Crisis Stabilization Centers (CSCs) offer a person-centered, community-based alternative to Emergency Departments for suicide prevention. CSCs may facilitate the expansion of the 988 Suicide Prevention Lifeline by providing callers with places to go in communities to receive treatment. However, new, recovery-focused psychological interventions for suicide prevention that can be rapidly implemented in CSCs are needed to be effective. This pilot study examines the feasibility, acceptability, and target engagement of the Toward Recovery, Hope, Interpersonal Connection, Values, and Engagement (i.e., THRIVE) for CSCs. THRIVE includes a psychotherapy group and peer-led recovery coaching calls after discharge. This project consists of three phases to adapt, pilot, and test THRIVE in CSCs in preparation for a full-scale effectiveness trial. In phase I, we will use the Model for Implementation Design and Impact (i.e., MADI) to adapt THRIVE to CSCs’ implementation needs (n = 25). In phase II, we will assess the feasibility and acceptability of THRIVE through CSC Stakeholder feedback and completing a pilot trial of THRIVE with CSC guests (n = 20). In phase III, we will complete a pilot randomized effectiveness trial of THRIVE (n = 162) to test the effectiveness of THRIVE on treatment initiation. We will also examine target engagement (i.e., as thwarted belongingness, and perceived burdensomeness) of the THRIVE intervention. Participants will be randomized to (a) Thrive + Discharge & Safety Planning as Usual (i.e., Intervention Arm): or (b) Discharge & Safety Planning as Usual (i.e., Control Arm). Participants complete assessments at baseline, discharge, 1 month, and 3 months. This protocol demonstrates strategies for involving community-based practice partners in research and is the first randomized controlled trial in a CSC sponsored by the National Institute of Mental Health (NIMH).
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spelling doaj-art-2f70e3d2adb04b49af26192284d7710a2025-08-20T02:41:23ZengElsevierContemporary Clinical Trials Communications2451-86542025-08-014610151110.1016/j.conctc.2025.101511Study protocol for a randomized controlled effectiveness trial of THRIVE group and peer coaching to promote suicide recovery in crisis stabilization centersJennifer D. Lockman0Anthony R. Pisani1M. Alexis Kirk2Kimberly A. Van Orden3Ian J. Cero4Margaret E. Balfour5Kristina Mossgraber6David Jacobowitz7Kenneth R. Conner8Department of Psychiatry and Behavioral Neurobiology, Depression and Suicide Center, University of Alabama at Birmingham, United States; Office of Research, Center for Clinical and Translational Science, University of Alabama at Birmingham, United States; Corresponding author. University of Alabama at Birmingham, Department of Psychiatry, Depression and Suicide Center, 1720 7th Avenue South, Birmingham, AL, 35294-0017, United States.Department of Psychiatry, Center for the Study and Prevention of Suicide, University of Rochester, United States; Department of Pediatrics, University of Rochester, United StatesIndependent Consultant, United StatesDepartment of Psychiatry, Center for the Study and Prevention of Suicide, University of Rochester, United StatesDepartment of Psychiatry, Center for the Study and Prevention of Suicide, University of Rochester, United StatesConnections Health Solutions, United States; Department of Psychiatry, University of Arizona, United StatesSafeSide Prevention, United StatesDepartment of Psychiatry, Center for the Study and Prevention of Suicide, University of Rochester, United StatesDepartment of Psychiatry, Center for the Study and Prevention of Suicide, University of Rochester, United StatesCrisis Stabilization Centers (CSCs) offer a person-centered, community-based alternative to Emergency Departments for suicide prevention. CSCs may facilitate the expansion of the 988 Suicide Prevention Lifeline by providing callers with places to go in communities to receive treatment. However, new, recovery-focused psychological interventions for suicide prevention that can be rapidly implemented in CSCs are needed to be effective. This pilot study examines the feasibility, acceptability, and target engagement of the Toward Recovery, Hope, Interpersonal Connection, Values, and Engagement (i.e., THRIVE) for CSCs. THRIVE includes a psychotherapy group and peer-led recovery coaching calls after discharge. This project consists of three phases to adapt, pilot, and test THRIVE in CSCs in preparation for a full-scale effectiveness trial. In phase I, we will use the Model for Implementation Design and Impact (i.e., MADI) to adapt THRIVE to CSCs’ implementation needs (n = 25). In phase II, we will assess the feasibility and acceptability of THRIVE through CSC Stakeholder feedback and completing a pilot trial of THRIVE with CSC guests (n = 20). In phase III, we will complete a pilot randomized effectiveness trial of THRIVE (n = 162) to test the effectiveness of THRIVE on treatment initiation. We will also examine target engagement (i.e., as thwarted belongingness, and perceived burdensomeness) of the THRIVE intervention. Participants will be randomized to (a) Thrive + Discharge & Safety Planning as Usual (i.e., Intervention Arm): or (b) Discharge & Safety Planning as Usual (i.e., Control Arm). Participants complete assessments at baseline, discharge, 1 month, and 3 months. This protocol demonstrates strategies for involving community-based practice partners in research and is the first randomized controlled trial in a CSC sponsored by the National Institute of Mental Health (NIMH).http://www.sciencedirect.com/science/article/pii/S2451865425000857Model for adaptation design and impactParticipatory action researchSuicide preventionSuicide recoveryPeer supportCrisis stabilization centers
spellingShingle Jennifer D. Lockman
Anthony R. Pisani
M. Alexis Kirk
Kimberly A. Van Orden
Ian J. Cero
Margaret E. Balfour
Kristina Mossgraber
David Jacobowitz
Kenneth R. Conner
Study protocol for a randomized controlled effectiveness trial of THRIVE group and peer coaching to promote suicide recovery in crisis stabilization centers
Contemporary Clinical Trials Communications
Model for adaptation design and impact
Participatory action research
Suicide prevention
Suicide recovery
Peer support
Crisis stabilization centers
title Study protocol for a randomized controlled effectiveness trial of THRIVE group and peer coaching to promote suicide recovery in crisis stabilization centers
title_full Study protocol for a randomized controlled effectiveness trial of THRIVE group and peer coaching to promote suicide recovery in crisis stabilization centers
title_fullStr Study protocol for a randomized controlled effectiveness trial of THRIVE group and peer coaching to promote suicide recovery in crisis stabilization centers
title_full_unstemmed Study protocol for a randomized controlled effectiveness trial of THRIVE group and peer coaching to promote suicide recovery in crisis stabilization centers
title_short Study protocol for a randomized controlled effectiveness trial of THRIVE group and peer coaching to promote suicide recovery in crisis stabilization centers
title_sort study protocol for a randomized controlled effectiveness trial of thrive group and peer coaching to promote suicide recovery in crisis stabilization centers
topic Model for adaptation design and impact
Participatory action research
Suicide prevention
Suicide recovery
Peer support
Crisis stabilization centers
url http://www.sciencedirect.com/science/article/pii/S2451865425000857
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