A Cell-Based Assay to Measure the Activity of the Complement Convertases

A Cell-Based Assay to Measure the Activity of the Complement Convertases

Introduction: The complement system serves as a crucial defense mechanism against invading pathogens; however, dysregulation of this system can result in harmful consequences. Central to the complement cascade are the classical pathway (CP) or lectin pathway (LP) and the alternative pathway (AP) con...

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Bibliographic Details
Main Authors: Małgorzata Stasiłojć, Grzegorz Stasiłojć, Alicja Kuźniewska, Santiago Rodriguez de Córdoba, Marcin Okrój
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Kidney International Reports
Subjects:
aHUS
C3G
complement system
convertase
eculizumab
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924016930
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