PATHOGENESIS, CLINICAL AND LABORATORY FEATURES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired progressive or relapse-remitting immunemediated disease of peripheral nervous system. CIDP has typical and atypical variants. Typical variant includes development of symmetric motor and sensory nerve fibers functions abnormaliti...
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| Format: | Article |
| Language: | Russian |
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Academician I.P. Pavlov First St. Petersburg State Medical University
2018-12-01
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| Series: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
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| Online Access: | https://www.sci-notes.ru/jour/article/view/519 |
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| _version_ | 1849689656173527040 |
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| author | R. A. Gapeshin E. R. Barantsevich A. A. Yakovlev |
| author_facet | R. A. Gapeshin E. R. Barantsevich A. A. Yakovlev |
| author_sort | R. A. Gapeshin |
| collection | DOAJ |
| description | Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired progressive or relapse-remitting immunemediated disease of peripheral nervous system. CIDP has typical and atypical variants. Typical variant includes development of symmetric motor and sensory nerve fibers functions abnormalities. The diagnosis of CIDP reveals on clinical presentation and electrophysiological data. There aren’t any biomarkers of such disease. Cerebrospinal fluid analysis, magnetic resonance tomography of peripheral nerves and nerve biopsy may be additional methods to confirm the diagnosis. Instead of international criteria of CIDP diagnosis and large variety of laboratory and instrumental methods, there are many difficulties to make the appropriate diagnosis. This review discusses current concepts of pathogenesis, clinical diagnostics and laboratory and instrumental methods used for differential diagnosis and confirmation of the diagnosis of CIDP and new areas in CIDP research. |
| format | Article |
| id | doaj-art-2f60d100ae854e6eba0673f5de832bd1 |
| institution | DOAJ |
| issn | 1607-4181 2541-8807 |
| language | Russian |
| publishDate | 2018-12-01 |
| publisher | Academician I.P. Pavlov First St. Petersburg State Medical University |
| record_format | Article |
| series | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
| spelling | doaj-art-2f60d100ae854e6eba0673f5de832bd12025-08-20T03:21:32ZrusAcademician I.P. Pavlov First St. Petersburg State Medical UniversityУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова1607-41812541-88072018-12-01253142410.24884/1607-4181-2018-25-3-14-24409PATHOGENESIS, CLINICAL AND LABORATORY FEATURES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHYR. A. Gapeshin0E. R. Barantsevich1A. A. Yakovlev2Pavlov University.Pavlov University.Pavlov University; Federal State Budgetary Educational Institution of Higher Education «North-Western State Medical University named after I. I. Mechnikov».Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired progressive or relapse-remitting immunemediated disease of peripheral nervous system. CIDP has typical and atypical variants. Typical variant includes development of symmetric motor and sensory nerve fibers functions abnormalities. The diagnosis of CIDP reveals on clinical presentation and electrophysiological data. There aren’t any biomarkers of such disease. Cerebrospinal fluid analysis, magnetic resonance tomography of peripheral nerves and nerve biopsy may be additional methods to confirm the diagnosis. Instead of international criteria of CIDP diagnosis and large variety of laboratory and instrumental methods, there are many difficulties to make the appropriate diagnosis. This review discusses current concepts of pathogenesis, clinical diagnostics and laboratory and instrumental methods used for differential diagnosis and confirmation of the diagnosis of CIDP and new areas in CIDP research.https://www.sci-notes.ru/jour/article/view/519chronic inflammatory demyelinating polyneuropathyautoimmune disorderelectroneuromyographydemyelinationcerebrospinal fluidmagnetic resonance tomography |
| spellingShingle | R. A. Gapeshin E. R. Barantsevich A. A. Yakovlev PATHOGENESIS, CLINICAL AND LABORATORY FEATURES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова chronic inflammatory demyelinating polyneuropathy autoimmune disorder electroneuromyography demyelination cerebrospinal fluid magnetic resonance tomography |
| title | PATHOGENESIS, CLINICAL AND LABORATORY FEATURES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY |
| title_full | PATHOGENESIS, CLINICAL AND LABORATORY FEATURES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY |
| title_fullStr | PATHOGENESIS, CLINICAL AND LABORATORY FEATURES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY |
| title_full_unstemmed | PATHOGENESIS, CLINICAL AND LABORATORY FEATURES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY |
| title_short | PATHOGENESIS, CLINICAL AND LABORATORY FEATURES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY |
| title_sort | pathogenesis clinical and laboratory features of chronic inflammatory demyelinating polyneuropathy |
| topic | chronic inflammatory demyelinating polyneuropathy autoimmune disorder electroneuromyography demyelination cerebrospinal fluid magnetic resonance tomography |
| url | https://www.sci-notes.ru/jour/article/view/519 |
| work_keys_str_mv | AT ragapeshin pathogenesisclinicalandlaboratoryfeaturesofchronicinflammatorydemyelinatingpolyneuropathy AT erbarantsevich pathogenesisclinicalandlaboratoryfeaturesofchronicinflammatorydemyelinatingpolyneuropathy AT aayakovlev pathogenesisclinicalandlaboratoryfeaturesofchronicinflammatorydemyelinatingpolyneuropathy |