The Association of BMI and TSH Levels with IVF/ICSI Outcomes

Objective: This study aimed to investigate the relationship between thyroid-stimulating hormone (TSH) levels, body mass index (BMI), and the success or failure of in vitro fertilization (IVF), as well as pregnancy outcomes in women undergoing IVF/ICSI treatment. Methods: In this case-control study...

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Main Authors: Soudabeh Sabetian, Zeinab Montaseri, Fatemeh Dadgar, Zahra Esfandiari, Sedighe Foruhari, Bahia Namavar Jahromi
Format: Article
Language:English
Published: Knowledge E 2025-03-01
Series:Journal of Infertility and Reproductive Biology
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Online Access:https://knepublishing.com/index.php/JIRB/article/view/18140
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author Soudabeh Sabetian
Zeinab Montaseri
Fatemeh Dadgar
Zahra Esfandiari
Sedighe Foruhari
Bahia Namavar Jahromi
author_facet Soudabeh Sabetian
Zeinab Montaseri
Fatemeh Dadgar
Zahra Esfandiari
Sedighe Foruhari
Bahia Namavar Jahromi
author_sort Soudabeh Sabetian
collection DOAJ
description Objective: This study aimed to investigate the relationship between thyroid-stimulating hormone (TSH) levels, body mass index (BMI), and the success or failure of in vitro fertilization (IVF), as well as pregnancy outcomes in women undergoing IVF/ICSI treatment. Methods: In this case-control study, data were collected from 278 infertile couples referred to infertility centers affiliated with Shiraz University of Medical Sciences between 2016 and 2023. Demographic variables, hormone levels, TSH, BMI, and additional factors such as infertility duration and varicocele status were analyzed. Statistical analysis was conducted using SPSS software. Results: Of the participants, 137 achieved successful IVF outcomes. BMI, TSH levels, and hypothyroidism were not significantly correlated with IVF/ICSI success or live birth rates. Secondary infertility cases demonstrated higher success rates, and men with untreated varicocele were linked to better IVF outcomes. Conclusion: BMI and TSH levels showed no significant association with IVF success or live birth outcomes. However, secondary infertility and untreated male varicocele were associated with improved pregnancy results. Further research with larger samples and detailed sub-categorization of infertility causes is recommended.
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series Journal of Infertility and Reproductive Biology
spelling doaj-art-2f5b709edf1a4fa282ee8db076ea3edf2025-08-20T03:50:31ZengKnowledge EJournal of Infertility and Reproductive Biology2310-75882025-03-0113110.18502/jirb.v13i1.18140The Association of BMI and TSH Levels with IVF/ICSI OutcomesSoudabeh Sabetian0 Zeinab Montaseri 1Fatemeh Dadgar2Zahra Esfandiari3Sedighe Foruhari4Bahia Namavar Jahromi5Infertility Research Center, Shiraz University of Medical Sciences, ShirazStudent Research Committee, Shiraz University of Medical Sciences, ShirazStudent Research Committee, Shiraz University of Medical Sciences, ShirazSchool of Science, Shiraz Branch, Islamic Azad University, ShirazInfertility Research Center, Shiraz University of Medical Sciences, ShirazInfertility Research Center, Shiraz University of Medical Sciences, Shiraz Objective: This study aimed to investigate the relationship between thyroid-stimulating hormone (TSH) levels, body mass index (BMI), and the success or failure of in vitro fertilization (IVF), as well as pregnancy outcomes in women undergoing IVF/ICSI treatment. Methods: In this case-control study, data were collected from 278 infertile couples referred to infertility centers affiliated with Shiraz University of Medical Sciences between 2016 and 2023. Demographic variables, hormone levels, TSH, BMI, and additional factors such as infertility duration and varicocele status were analyzed. Statistical analysis was conducted using SPSS software. Results: Of the participants, 137 achieved successful IVF outcomes. BMI, TSH levels, and hypothyroidism were not significantly correlated with IVF/ICSI success or live birth rates. Secondary infertility cases demonstrated higher success rates, and men with untreated varicocele were linked to better IVF outcomes. Conclusion: BMI and TSH levels showed no significant association with IVF success or live birth outcomes. However, secondary infertility and untreated male varicocele were associated with improved pregnancy results. Further research with larger samples and detailed sub-categorization of infertility causes is recommended. https://knepublishing.com/index.php/JIRB/article/view/18140pregnancybody mass indexthyroid-stimulating hormonein vitro fertilization
spellingShingle Soudabeh Sabetian
Zeinab Montaseri
Fatemeh Dadgar
Zahra Esfandiari
Sedighe Foruhari
Bahia Namavar Jahromi
The Association of BMI and TSH Levels with IVF/ICSI Outcomes
Journal of Infertility and Reproductive Biology
pregnancy
body mass index
thyroid-stimulating hormone
in vitro fertilization
title The Association of BMI and TSH Levels with IVF/ICSI Outcomes
title_full The Association of BMI and TSH Levels with IVF/ICSI Outcomes
title_fullStr The Association of BMI and TSH Levels with IVF/ICSI Outcomes
title_full_unstemmed The Association of BMI and TSH Levels with IVF/ICSI Outcomes
title_short The Association of BMI and TSH Levels with IVF/ICSI Outcomes
title_sort association of bmi and tsh levels with ivf icsi outcomes
topic pregnancy
body mass index
thyroid-stimulating hormone
in vitro fertilization
url https://knepublishing.com/index.php/JIRB/article/view/18140
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