Cirrhosis Management: Utilization and Optimizing Non-Invasive Tests in Portal Hypertension
Early identification of clinically significant portal hypertension (CSPH) is crucial in cirrhosis, as it is the primary underlying mechanism of cirrhosis complications. One such complication is esophageal varices, which are associated with high morbidity and mortality. Hepatic venous pressure gradi...
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| Language: | English |
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Interna Publishing
2024-10-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/2897 |
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| author | Irsan Hasan |
| author_facet | Irsan Hasan |
| author_sort | Irsan Hasan |
| collection | DOAJ |
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Early identification of clinically significant portal hypertension (CSPH) is crucial in cirrhosis, as it is the primary underlying mechanism of cirrhosis complications. One such complication is esophageal varices, which are associated with high morbidity and mortality. Hepatic venous pressure gradient (HVPG) measurements and endoscopy, considered the gold standard for these conditions, are invasive methods that are limited, costly, and inconvenient. To address this challenge, a combination of non-invasive tests can be employed to predict CSPH and esophageal varices. A validated approach involves combining liver stiffness measurement (LSM) by transient elastography (TE) with platelet count. Additionally, spleen stiffness measurement (SSM) has emerged as a promising method for evaluating high-risk varices, as reported by Nababan et al. Therefore, non-invasive methods can be utilized to identify patients who need invasive procedures or potentially replace invasive procedures altogether.
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| format | Article |
| id | doaj-art-2f5b20859b3b423983d5915a23c8d97e |
| institution | OA Journals |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-2f5b20859b3b423983d5915a23c8d97e2025-08-20T02:37:14ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322024-10-01563Cirrhosis Management: Utilization and Optimizing Non-Invasive Tests in Portal HypertensionIrsan Hasan0Division of Hepatobiliary, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Early identification of clinically significant portal hypertension (CSPH) is crucial in cirrhosis, as it is the primary underlying mechanism of cirrhosis complications. One such complication is esophageal varices, which are associated with high morbidity and mortality. Hepatic venous pressure gradient (HVPG) measurements and endoscopy, considered the gold standard for these conditions, are invasive methods that are limited, costly, and inconvenient. To address this challenge, a combination of non-invasive tests can be employed to predict CSPH and esophageal varices. A validated approach involves combining liver stiffness measurement (LSM) by transient elastography (TE) with platelet count. Additionally, spleen stiffness measurement (SSM) has emerged as a promising method for evaluating high-risk varices, as reported by Nababan et al. Therefore, non-invasive methods can be utilized to identify patients who need invasive procedures or potentially replace invasive procedures altogether. http://www.actamedindones.org/index.php/ijim/article/view/2897Cirrhosisendoscopyesophageal variceshepatic venous pressure gradientportal hypertensionliver stiffness |
| spellingShingle | Irsan Hasan Cirrhosis Management: Utilization and Optimizing Non-Invasive Tests in Portal Hypertension Acta Medica Indonesiana Cirrhosis endoscopy esophageal varices hepatic venous pressure gradient portal hypertension liver stiffness |
| title | Cirrhosis Management: Utilization and Optimizing Non-Invasive Tests in Portal Hypertension |
| title_full | Cirrhosis Management: Utilization and Optimizing Non-Invasive Tests in Portal Hypertension |
| title_fullStr | Cirrhosis Management: Utilization and Optimizing Non-Invasive Tests in Portal Hypertension |
| title_full_unstemmed | Cirrhosis Management: Utilization and Optimizing Non-Invasive Tests in Portal Hypertension |
| title_short | Cirrhosis Management: Utilization and Optimizing Non-Invasive Tests in Portal Hypertension |
| title_sort | cirrhosis management utilization and optimizing non invasive tests in portal hypertension |
| topic | Cirrhosis endoscopy esophageal varices hepatic venous pressure gradient portal hypertension liver stiffness |
| url | http://www.actamedindones.org/index.php/ijim/article/view/2897 |
| work_keys_str_mv | AT irsanhasan cirrhosismanagementutilizationandoptimizingnoninvasivetestsinportalhypertension |