C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease

A case of C1 inhibitor deficiency presenting as localized edema of the small intestine is described. A 16-year-old, previously healthy woman presented with recurrent attacks of abdominal pain and vomiting following minor abdominal trauma. Investigations including computed tomography scan and barium...

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Main Authors: Kelly W Burak, Gary R May
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2000/414107
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author Kelly W Burak
Gary R May
author_facet Kelly W Burak
Gary R May
author_sort Kelly W Burak
collection DOAJ
description A case of C1 inhibitor deficiency presenting as localized edema of the small intestine is described. A 16-year-old, previously healthy woman presented with recurrent attacks of abdominal pain and vomiting following minor abdominal trauma. Investigations including computed tomography scan and barium studies confirmed localized edema of the jejunum. At laparoscopy, Crohn’s disease was suspected; however, a subsequent enteroscopy was normal. Complement levels revealed a low C4 level, and C1 inhibitor deficiency was later confirmed. Attacks of abdominal pain began after starting oral contraceptives and have not returned since stopping the birth control pill. This rare cause of abdominal pain is examined, and C1 inhibitor deficiency and angioedema are reviewed.
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spelling doaj-art-2f59ef81011349f5b8dfd0014ccd0c172025-02-03T01:03:38ZengWileyCanadian Journal of Gastroenterology0835-79002000-01-0114434935110.1155/2000/414107C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s DiseaseKelly W Burak0Gary R May1Department of Medicine, University of Calgary, Calgary, Alberta, CanadaDepartment of Medicine, University of Calgary, Calgary, Alberta, CanadaA case of C1 inhibitor deficiency presenting as localized edema of the small intestine is described. A 16-year-old, previously healthy woman presented with recurrent attacks of abdominal pain and vomiting following minor abdominal trauma. Investigations including computed tomography scan and barium studies confirmed localized edema of the jejunum. At laparoscopy, Crohn’s disease was suspected; however, a subsequent enteroscopy was normal. Complement levels revealed a low C4 level, and C1 inhibitor deficiency was later confirmed. Attacks of abdominal pain began after starting oral contraceptives and have not returned since stopping the birth control pill. This rare cause of abdominal pain is examined, and C1 inhibitor deficiency and angioedema are reviewed.http://dx.doi.org/10.1155/2000/414107
spellingShingle Kelly W Burak
Gary R May
C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease
Canadian Journal of Gastroenterology
title C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease
title_full C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease
title_fullStr C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease
title_full_unstemmed C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease
title_short C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease
title_sort c1 inhibitor deficiency and angioedema of the small intestine masquerading as crohn s disease
url http://dx.doi.org/10.1155/2000/414107
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