A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data

Computational models of cardiac electrophysiology have gradually matured during the past few decades and are now being personalised to provide patient-specific therapy guidance for improving suboptimal treatment outcomes. The predictive features of these personalised electrophysiology models hold th...

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Main Authors: Ovais A Jaffery, Lea Melki, Gregory Slabaugh, Wilson W Good, Caroline H Roney
Format: Article
Language:English
Published: Radcliffe Medical Media 2024-05-01
Series:Arrhythmia & Electrophysiology Review
Online Access:https://www.aerjournal.com/articleindex/aer.2023.25
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author Ovais A Jaffery
Lea Melki
Gregory Slabaugh
Wilson W Good
Caroline H Roney
author_facet Ovais A Jaffery
Lea Melki
Gregory Slabaugh
Wilson W Good
Caroline H Roney
author_sort Ovais A Jaffery
collection DOAJ
description Computational models of cardiac electrophysiology have gradually matured during the past few decades and are now being personalised to provide patient-specific therapy guidance for improving suboptimal treatment outcomes. The predictive features of these personalised electrophysiology models hold the promise of providing optimal treatment planning, which is currently limited in the clinic owing to reliance on a population-based or average patient approach. The generation of a personalised electrophysiology model entails a sequence of steps for which a range of activation mapping, calibration methods and therapy simulation pipelines have been suggested. However, the optimal methods that can potentially constitute a clinically relevant in silico treatment are still being investigated and face limitations, such as uncertainty of electroanatomical data recordings, generation and calibration of models within clinical timelines and requirements to validate or benchmark the recovered tissue parameters. This paper is aimed at reporting techniques on the personalisation of cardiac computational models, with a focus on calibrating cardiac tissue conductivity based on electroanatomical mapping data.
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2050-3377
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publishDate 2024-05-01
publisher Radcliffe Medical Media
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series Arrhythmia & Electrophysiology Review
spelling doaj-art-2f504fabc521456a99bfd7b5920e8d5f2025-08-20T01:56:38ZengRadcliffe Medical MediaArrhythmia & Electrophysiology Review2050-33692050-33772024-05-011310.15420/aer.2023.25A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping DataOvais A Jaffery0Lea Melki1Gregory Slabaugh2Wilson W Good3Caroline H Roney4School of Engineering and Materials Science, Queen Mary University of London, London, UKR&D Algorithms, Acutus Medical, Carlsbad, CA, USDigital Environment Research Institute, Queen Mary University of London, London, UKR&D Algorithms, Acutus Medical, Carlsbad, CA, USSchool of Engineering and Materials Science, Queen Mary University of London, London, UKComputational models of cardiac electrophysiology have gradually matured during the past few decades and are now being personalised to provide patient-specific therapy guidance for improving suboptimal treatment outcomes. The predictive features of these personalised electrophysiology models hold the promise of providing optimal treatment planning, which is currently limited in the clinic owing to reliance on a population-based or average patient approach. The generation of a personalised electrophysiology model entails a sequence of steps for which a range of activation mapping, calibration methods and therapy simulation pipelines have been suggested. However, the optimal methods that can potentially constitute a clinically relevant in silico treatment are still being investigated and face limitations, such as uncertainty of electroanatomical data recordings, generation and calibration of models within clinical timelines and requirements to validate or benchmark the recovered tissue parameters. This paper is aimed at reporting techniques on the personalisation of cardiac computational models, with a focus on calibrating cardiac tissue conductivity based on electroanatomical mapping data.https://www.aerjournal.com/articleindex/aer.2023.25
spellingShingle Ovais A Jaffery
Lea Melki
Gregory Slabaugh
Wilson W Good
Caroline H Roney
A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data
Arrhythmia & Electrophysiology Review
title A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data
title_full A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data
title_fullStr A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data
title_full_unstemmed A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data
title_short A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data
title_sort review of personalised cardiac computational modelling using electroanatomical mapping data
url https://www.aerjournal.com/articleindex/aer.2023.25
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