Altered mental status caused by hypertriglyceridemia in an adolescent
A long list of diseases and disorders can result in altered mental status in pediatric-aged patients including neurologic, infectious, toxicological, traumatic, metabolic, and psychiatric etiologies. Laboratory testing and radiologic imaging is frequently necessary to further narrow the differen...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Pediatric Anesthesia and Critical Care Journal
2024-12-01
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| Series: | Pediatric Anesthesia and Critical Care Journal (PACCJ) |
| Subjects: | |
| Online Access: | http://www.anestesiarianimazione.com/PACCJ%202024/Altered%20mental%20status%20caused%20by%20hypertriglyceridemia%20in%20an%20adolescent%20.pdf |
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| Summary: | A long list of diseases and disorders can result in altered
mental status in pediatric-aged patients including neurologic,
infectious, toxicological, traumatic, metabolic, and
psychiatric etiologies. Laboratory testing and radiologic
imaging is frequently necessary to further narrow the differential
diagnosis. We present a 13-year-old adolescent
who presented with altered mental status that was originally
attributed to metabolic derangements associated
with diabetic ketoacidosis. The subsequent laboratory
work-up demonstrated lipemic serum with profound hypertriglyceridemia,
which was eventually thought to be
the etiology of his altered mental status. As treatment resulted
in correction of the hypertriglyceridemia, his mental
status improved and returned to baseline. The pathophysiology
of lipid metabolism is reviewed, etiology of
hypertriglyceridemia presented, and mechanisms for its
role in altered mental status discussed. |
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| ISSN: | 2281-8421 |