Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical Implications
A solitary fibrous tumor (SFT) arising in the paratesticular region is a rare event. Typically most SFTs present as a lung mass and have a characteristic microscopic appearance. Although uncommon, SFTs may present at just about any anatomical site. Here we present a case of a SFT arising along the r...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2018/7462032 |
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| author | Christopher P. Marquez Haiyan Zhang Jason Goodrum J. Nicholas Sreshta Marjan Afrouzian |
| author_facet | Christopher P. Marquez Haiyan Zhang Jason Goodrum J. Nicholas Sreshta Marjan Afrouzian |
| author_sort | Christopher P. Marquez |
| collection | DOAJ |
| description | A solitary fibrous tumor (SFT) arising in the paratesticular region is a rare event. Typically most SFTs present as a lung mass and have a characteristic microscopic appearance. Although uncommon, SFTs may present at just about any anatomical site. Here we present a case of a SFT arising along the right spermatic cord, with histologic features mimicking a cellular angiofibroma. We describe the diagnostic immunohistochemical markers useful for arriving at its diagnosis. We also summarize our current understanding of the structural and molecular features that make up SFTs and discuss how these features may help us better understand the pathophysiology of pluripotent mesenchymal stem cell differentiation. |
| format | Article |
| id | doaj-art-2f437e2bf01f45aa86917b4ec0c81247 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-2f437e2bf01f45aa86917b4ec0c812472025-02-03T01:02:52ZengWileyCase Reports in Pathology2090-67812090-679X2018-01-01201810.1155/2018/74620327462032Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical ImplicationsChristopher P. Marquez0Haiyan Zhang1Jason Goodrum2J. Nicholas Sreshta3Marjan Afrouzian4Department of Pathology, University of Texas Medical Branch, Galveston, TX, USADepartment of Pathology, University of Texas Medical Branch, Galveston, TX, USADepartment of Surgery, Division of Urology, University of Texas Medical Branch, Galveston, TX, USADepartment of Surgery, Division of Urology, University of Texas Medical Branch, Galveston, TX, USADepartment of Pathology, University of Texas Medical Branch, Galveston, TX, USAA solitary fibrous tumor (SFT) arising in the paratesticular region is a rare event. Typically most SFTs present as a lung mass and have a characteristic microscopic appearance. Although uncommon, SFTs may present at just about any anatomical site. Here we present a case of a SFT arising along the right spermatic cord, with histologic features mimicking a cellular angiofibroma. We describe the diagnostic immunohistochemical markers useful for arriving at its diagnosis. We also summarize our current understanding of the structural and molecular features that make up SFTs and discuss how these features may help us better understand the pathophysiology of pluripotent mesenchymal stem cell differentiation.http://dx.doi.org/10.1155/2018/7462032 |
| spellingShingle | Christopher P. Marquez Haiyan Zhang Jason Goodrum J. Nicholas Sreshta Marjan Afrouzian Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical Implications Case Reports in Pathology |
| title | Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical Implications |
| title_full | Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical Implications |
| title_fullStr | Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical Implications |
| title_full_unstemmed | Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical Implications |
| title_short | Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical Implications |
| title_sort | florid proliferation of hyalinized vessels in a spermatic cord stat6 positive solitary fibrous tumor and its potential clinical implications |
| url | http://dx.doi.org/10.1155/2018/7462032 |
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