Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element Analysis

Lumbar interbody fusion (LIF) is a standard treatment for spinal instability, yet postoperative subsidence and adjacent segment degeneration (ASD) remain critical challenges. This study evaluates the biomechanical efficacy of personalized porous fusion cages—featuring Gyroid (G-Cage) and Voronoi (V-...

Full description

Saved in:
Bibliographic Details
Main Authors: Chenkai Zhu, Kan Deng, Zhenzong Shao, Yong Wang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/15/10/5384
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850257728076775424
author Chenkai Zhu
Kan Deng
Zhenzong Shao
Yong Wang
author_facet Chenkai Zhu
Kan Deng
Zhenzong Shao
Yong Wang
author_sort Chenkai Zhu
collection DOAJ
description Lumbar interbody fusion (LIF) is a standard treatment for spinal instability, yet postoperative subsidence and adjacent segment degeneration (ASD) remain critical challenges. This study evaluates the biomechanical efficacy of personalized porous fusion cages—featuring Gyroid (G-Cage) and Voronoi (V-Cage) architectures—against classic (C-Cage) and personalized (P-Cage) designs, aiming to enhance stability and mitigate subsidence risks. A finite element model of the L3–L4 segment, derived from CT scans of a healthy male volunteer, was developed to simulate six motion modes (compression, rotation, flexion, extension, and left/right bending). Biomechanical parameters, including range of motion (ROM), cage stress, endplate stress, and displacement, were analyzed. The results demonstrated that the V-Cage exhibited superior performance, reducing ROM by 51% in extension, cage stress by 41.7% in compression, and endplate stress by 63.7% in right bending compared to the C-Cage. The porous designs (G-Cage, V-Cage) exhibited biomimetic stress distribution and minimized micromotion, which was attributed to their trabecular-like architectures. These findings highlight the Voronoi-based porous cage as a biomechanically optimized solution, offering enhanced stability and reduced subsidence risk when compared to classic implants. The study underscores the potential of patient-specific porous designs in advancing LIF outcomes, warranting further clinical validation to translate computational insights into practical applications.
format Article
id doaj-art-2f3b8b154d144efd9fc657726bbc8dec
institution OA Journals
issn 2076-3417
language English
publishDate 2025-05-01
publisher MDPI AG
record_format Article
series Applied Sciences
spelling doaj-art-2f3b8b154d144efd9fc657726bbc8dec2025-08-20T01:56:20ZengMDPI AGApplied Sciences2076-34172025-05-011510538410.3390/app15105384Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element AnalysisChenkai Zhu0Kan Deng1Zhenzong Shao2Yong Wang3Ningbo Institute of Technology, Beihang University, 399 Kangda Road, Ningbo 315832, ChinaNingbo Institute of Technology, Beihang University, 399 Kangda Road, Ningbo 315832, ChinaNingbo Institute of Technology, Beihang University, 399 Kangda Road, Ningbo 315832, ChinaNingbo Institute of Technology, Beihang University, 399 Kangda Road, Ningbo 315832, ChinaLumbar interbody fusion (LIF) is a standard treatment for spinal instability, yet postoperative subsidence and adjacent segment degeneration (ASD) remain critical challenges. This study evaluates the biomechanical efficacy of personalized porous fusion cages—featuring Gyroid (G-Cage) and Voronoi (V-Cage) architectures—against classic (C-Cage) and personalized (P-Cage) designs, aiming to enhance stability and mitigate subsidence risks. A finite element model of the L3–L4 segment, derived from CT scans of a healthy male volunteer, was developed to simulate six motion modes (compression, rotation, flexion, extension, and left/right bending). Biomechanical parameters, including range of motion (ROM), cage stress, endplate stress, and displacement, were analyzed. The results demonstrated that the V-Cage exhibited superior performance, reducing ROM by 51% in extension, cage stress by 41.7% in compression, and endplate stress by 63.7% in right bending compared to the C-Cage. The porous designs (G-Cage, V-Cage) exhibited biomimetic stress distribution and minimized micromotion, which was attributed to their trabecular-like architectures. These findings highlight the Voronoi-based porous cage as a biomechanically optimized solution, offering enhanced stability and reduced subsidence risk when compared to classic implants. The study underscores the potential of patient-specific porous designs in advancing LIF outcomes, warranting further clinical validation to translate computational insights into practical applications.https://www.mdpi.com/2076-3417/15/10/5384lumbar interbody fusionfinite element analysisVoronoi porous structuresubsidence riskadjacent segment degeneration
spellingShingle Chenkai Zhu
Kan Deng
Zhenzong Shao
Yong Wang
Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element Analysis
Applied Sciences
lumbar interbody fusion
finite element analysis
Voronoi porous structure
subsidence risk
adjacent segment degeneration
title Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element Analysis
title_full Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element Analysis
title_fullStr Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element Analysis
title_full_unstemmed Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element Analysis
title_short Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element Analysis
title_sort biomechanical optimization of lumbar fusion cages with a porous design a finite element analysis
topic lumbar interbody fusion
finite element analysis
Voronoi porous structure
subsidence risk
adjacent segment degeneration
url https://www.mdpi.com/2076-3417/15/10/5384
work_keys_str_mv AT chenkaizhu biomechanicaloptimizationoflumbarfusioncageswithaporousdesignafiniteelementanalysis
AT kandeng biomechanicaloptimizationoflumbarfusioncageswithaporousdesignafiniteelementanalysis
AT zhenzongshao biomechanicaloptimizationoflumbarfusioncageswithaporousdesignafiniteelementanalysis
AT yongwang biomechanicaloptimizationoflumbarfusioncageswithaporousdesignafiniteelementanalysis