Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography

Purpose. To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF) underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods. Twenty participants (4 males and 16 females, 23.0 ± 3.7...

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Main Authors: Lele Cui, Sisi Chen, Weihe Zhou, Kaixuan Sheng, Lei Zhang, Meixiao Shen, Ming Li
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2018/3463595
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author Lele Cui
Sisi Chen
Weihe Zhou
Kaixuan Sheng
Lei Zhang
Meixiao Shen
Ming Li
author_facet Lele Cui
Sisi Chen
Weihe Zhou
Kaixuan Sheng
Lei Zhang
Meixiao Shen
Ming Li
author_sort Lele Cui
collection DOAJ
description Purpose. To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF) underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods. Twenty participants (4 males and 16 females, 23.0 ± 3.7 years) were fitted with two different types of soft contact lenses randomly. The limbus with lens was imaged with the UHR-OCT at the horizontal meridian every two hours up to 6 hours during lens wear. The conjunctival overlap was ranked as the percentage of the edge covered by the conjunctiva. The frequency of occurrence for visualized peripheral PoLTF was determined. Results. The average conjunctival overlaps at insertion were 49% and 73% for galyfilcon A and balafilcon A lenses and increased significantly to 84% and 90% by 6 hours of lens wear (P<0.001). Lenses with rounded edges had more conjunctival overlap than the lenses with angled edges (P=0.014). There were significant decreases for PoLTF on the conjunctiva (P=0.014) and peripheral cornea (P=0.004) over the study period compared to insertion. The percentage of subjects with PoLTF on the conjunctiva (32.5%) and peripheral cornea (36%) were greater in subjects wearing balafilcon A lenses (P=0.017). Conclusions. Increased conjunctival overlap over the lens edges and reduced PoLTF underneath the peripheral region of soft contact lenses were shown during lens daily wear. The lens edge configuration may play a role in conjunctival response and peripheral PoLTF.
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spelling doaj-art-2f318fe29b3a4562b2650ca694827e5f2025-08-20T02:08:12ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/34635953463595Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence TomographyLele Cui0Sisi Chen1Weihe Zhou2Kaixuan Sheng3Lei Zhang4Meixiao Shen5Ming Li6Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaNingbo Aier Guangming Eye Hosptial, Ningbo, Zhejiang, ChinaEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaPurpose. To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF) underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods. Twenty participants (4 males and 16 females, 23.0 ± 3.7 years) were fitted with two different types of soft contact lenses randomly. The limbus with lens was imaged with the UHR-OCT at the horizontal meridian every two hours up to 6 hours during lens wear. The conjunctival overlap was ranked as the percentage of the edge covered by the conjunctiva. The frequency of occurrence for visualized peripheral PoLTF was determined. Results. The average conjunctival overlaps at insertion were 49% and 73% for galyfilcon A and balafilcon A lenses and increased significantly to 84% and 90% by 6 hours of lens wear (P<0.001). Lenses with rounded edges had more conjunctival overlap than the lenses with angled edges (P=0.014). There were significant decreases for PoLTF on the conjunctiva (P=0.014) and peripheral cornea (P=0.004) over the study period compared to insertion. The percentage of subjects with PoLTF on the conjunctiva (32.5%) and peripheral cornea (36%) were greater in subjects wearing balafilcon A lenses (P=0.017). Conclusions. Increased conjunctival overlap over the lens edges and reduced PoLTF underneath the peripheral region of soft contact lenses were shown during lens daily wear. The lens edge configuration may play a role in conjunctival response and peripheral PoLTF.http://dx.doi.org/10.1155/2018/3463595
spellingShingle Lele Cui
Sisi Chen
Weihe Zhou
Kaixuan Sheng
Lei Zhang
Meixiao Shen
Ming Li
Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography
Journal of Ophthalmology
title Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography
title_full Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography
title_fullStr Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography
title_full_unstemmed Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography
title_short Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography
title_sort characterization of soft contact lens edge fitting during daily wear using ultrahigh resolution optical coherence tomography
url http://dx.doi.org/10.1155/2018/3463595
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