Phytochemical Constituents from <i>Globimetula oreophila</i> as Plasmepsin I and II Inhibitors in Antimalarial Drug Discovery: An In Silico Approach

Phytochemical Constituents from <i>Globimetula oreophila</i> as Plasmepsin I and II Inhibitors in Antimalarial Drug Discovery: An In Silico Approach

Malaria remains a critical global health challenge, particularly affecting Sub-Saharan Africa. Plasmepsins, vital in hydrolyzing peptide bonds within proteins, present promising targets for antimalarial drugs. Plasmepsins I and II, key aspartic proteases, are crucial in various parasite processes. T...

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Bibliographic Details
Main Authors: Dauda Garba, Bila Hassan Ali, Bashar Bawa, Abdullahi Maryam, Hamza Asmau Nasiru, Yahaya Mohammed Sani, Muhammad Garba Magaji, Musa Isma’il Abdullahi, Aliyu Muhammad Musa, Hassan Halimatu Sadiya
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Chemistry Proceedings
Subjects:
<i>Globimetula oreophila</i>
malaria
molecular docking
<i>Plasmoidum falciparum</i>
phytochemicals
plasmepsin
Online Access:https://www.mdpi.com/2673-4583/16/1/42
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