Risks of Misinterpretation in the Evaluation of the Effect of Fruit-Based Drinks in Postprandial Studies

It has been suggested that some fruit-based drinks (FBD) may delay the onset of postprandial stress, which is involved in the pathogenesis of many diseases. The majority of the studies, which have investigated the effects of FBD on postprandial stress, involved a placebo that was a drink with the sa...

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Main Authors: Ilaria Peluso, Maura Palmery
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2014/870547
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author Ilaria Peluso
Maura Palmery
author_facet Ilaria Peluso
Maura Palmery
author_sort Ilaria Peluso
collection DOAJ
description It has been suggested that some fruit-based drinks (FBD) may delay the onset of postprandial stress, which is involved in the pathogenesis of many diseases. The majority of the studies, which have investigated the effects of FBD on postprandial stress, involved a placebo that was a drink with the same content in sugars or carbohydrates of the FBD, but without the bioactive antioxidant compounds. These studies were aimed more at evaluating the effect of the antioxidants rather than the effect of the FBD as a whole. Only 4 studies compared the effect of FBD with water as control and did not support the hypothesis that FBD could inhibit postprandial dysmetabolism, as well as the studies that compared the effect of orange juice and cola. Overall, the results suggest a complex relationship between postprandial dysmetabolism, inflammation, and oxidative stress. Furthermore, the inflammatory and oxidative stress markers need further analytical validation and normal ranges should be established in order to reach a firm conclusion. Finally, caution should be taken in the interpretation of the effect of FBD in postprandial studies and the reviewed results suggest that dietary recommendations should aim to limit rather than increase sugar-sweetened beverages consumption.
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spelling doaj-art-2f2fb7c53c194549a28bcda1175012082025-08-20T02:08:11ZengWileyGastroenterology Research and Practice1687-61211687-630X2014-01-01201410.1155/2014/870547870547Risks of Misinterpretation in the Evaluation of the Effect of Fruit-Based Drinks in Postprandial StudiesIlaria Peluso0Maura Palmery1Food and Nutrition Center of the Agricultural Research Council (CRA-NUT), Via Ardeatina 546, 00178 Rome, ItalyDepartment of Physiology and Pharmacology “V. Erspamer”, “Sapienza” University of Rome, Piazzale Aldo Moro 5, 00185 Rome, ItalyIt has been suggested that some fruit-based drinks (FBD) may delay the onset of postprandial stress, which is involved in the pathogenesis of many diseases. The majority of the studies, which have investigated the effects of FBD on postprandial stress, involved a placebo that was a drink with the same content in sugars or carbohydrates of the FBD, but without the bioactive antioxidant compounds. These studies were aimed more at evaluating the effect of the antioxidants rather than the effect of the FBD as a whole. Only 4 studies compared the effect of FBD with water as control and did not support the hypothesis that FBD could inhibit postprandial dysmetabolism, as well as the studies that compared the effect of orange juice and cola. Overall, the results suggest a complex relationship between postprandial dysmetabolism, inflammation, and oxidative stress. Furthermore, the inflammatory and oxidative stress markers need further analytical validation and normal ranges should be established in order to reach a firm conclusion. Finally, caution should be taken in the interpretation of the effect of FBD in postprandial studies and the reviewed results suggest that dietary recommendations should aim to limit rather than increase sugar-sweetened beverages consumption.http://dx.doi.org/10.1155/2014/870547
spellingShingle Ilaria Peluso
Maura Palmery
Risks of Misinterpretation in the Evaluation of the Effect of Fruit-Based Drinks in Postprandial Studies
Gastroenterology Research and Practice
title Risks of Misinterpretation in the Evaluation of the Effect of Fruit-Based Drinks in Postprandial Studies
title_full Risks of Misinterpretation in the Evaluation of the Effect of Fruit-Based Drinks in Postprandial Studies
title_fullStr Risks of Misinterpretation in the Evaluation of the Effect of Fruit-Based Drinks in Postprandial Studies
title_full_unstemmed Risks of Misinterpretation in the Evaluation of the Effect of Fruit-Based Drinks in Postprandial Studies
title_short Risks of Misinterpretation in the Evaluation of the Effect of Fruit-Based Drinks in Postprandial Studies
title_sort risks of misinterpretation in the evaluation of the effect of fruit based drinks in postprandial studies
url http://dx.doi.org/10.1155/2014/870547
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