Perturbation of EPHA2 and EFNA1 trans binding amplifies inflammatory response in airway epithelial cells

Perturbation of EPHA2 and EFNA1 trans binding amplifies inflammatory response in airway epithelial cells

Summary: The interactions between EPH receptors and ephrin (EFN) ligands play a crucial role in maintaining epithelial integrity and aiding in defense against infections. However, it remains unclear how the EPH-EFN trans-binding changes during infections and how this alteration affects inflammatory...

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Bibliographic Details
Main Authors: Ryosuke Fukuda, Shiori Beppu, Daichi Hinata, Yuka Kamada, Tsukasa Okiyoneda
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
Subjects:
Biological sciences
Biochemistry
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225001324
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