Impaired Iron–Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy
Abstract Diabetic cardiomyopathy (DCM), a severe complication of diabetes, is characterized by mitochondrial dysfunction, oxidative stress, and DNA damage. Despite its severity, the intrinsic factors governing cardiomyocyte damage in DCM remain unclear. It is hypothesized that impaired iron–sulfur (...
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| Main Authors: | Mengyi Wang, Shiwu Zhang, Jinwei Tian, Fan Yang, He Chen, Shuzhi Bai, Jiaxin Kang, Kemiao Pang, Jiayi Huang, Mingjie Dong, Shiyun Dong, Zhen Tian, Shaohong Fang, Huitao Fan, Fanghao Lu, Bo Yu, Shuijie Li, Weihua Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202406695 |
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