Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review
Five-membered heterocycles, like isoxazolines, are an important class of compounds of bioorganic and pharmacological importance. They have been treated as useful intermediates for the transformation of a large number of bioactive molecules. It was known that these classes of compounds have diffe...
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College of science, university of Diyala
2024-01-01
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| Series: | Academic Science Journal |
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| Online Access: | https://acadscij.uodiyala.edu.iq/index.php/Home/article/view/62 |
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| author | mohammed alwan |
| author_facet | mohammed alwan |
| author_sort | mohammed alwan |
| collection | DOAJ |
| description |
Five-membered heterocycles, like isoxazolines, are an important class of compounds of bioorganic and pharmacological importance. They have been treated as useful intermediates for the transformation of a large number of bioactive molecules.
It was known that these classes of compounds have different biological activities. In this review, we discuss synthetic methods that are useful as building blocks for the synthesis of bioactive molecules and the medical application of isoxazoline systems.
The large number of studies described in this summary shows a wide range of pharmacological activities of isoxazole derivatives.
The pharmaceutical profiles of these new generations of isoxazoline would represent a fruitful matrix for the further development of the isoxazoline core, which could be a leading core for future developments to obtain safer and more effective therapies.
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| format | Article |
| id | doaj-art-2f217f0c8dfa43b1bf2d414f415d3993 |
| institution | Kabale University |
| issn | 2958-4612 2959-5568 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | College of science, university of Diyala |
| record_format | Article |
| series | Academic Science Journal |
| spelling | doaj-art-2f217f0c8dfa43b1bf2d414f415d39932024-11-19T10:00:24ZengCollege of science, university of DiyalaAcademic Science Journal2958-46122959-55682024-01-012110.24237/ASJ.02.01.742CSynthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini reviewmohammed alwan0diyala university - college of science Five-membered heterocycles, like isoxazolines, are an important class of compounds of bioorganic and pharmacological importance. They have been treated as useful intermediates for the transformation of a large number of bioactive molecules. It was known that these classes of compounds have different biological activities. In this review, we discuss synthetic methods that are useful as building blocks for the synthesis of bioactive molecules and the medical application of isoxazoline systems. The large number of studies described in this summary shows a wide range of pharmacological activities of isoxazole derivatives. The pharmaceutical profiles of these new generations of isoxazoline would represent a fruitful matrix for the further development of the isoxazoline core, which could be a leading core for future developments to obtain safer and more effective therapies. https://acadscij.uodiyala.edu.iq/index.php/Home/article/view/62Heterocyclic compounds, Isoxazoline, Biological activities, Anticancer activity, Antioxidant activity. |
| spellingShingle | mohammed alwan Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review Academic Science Journal Heterocyclic compounds, Isoxazoline, Biological activities, Anticancer activity, Antioxidant activity. |
| title | Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review |
| title_full | Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review |
| title_fullStr | Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review |
| title_full_unstemmed | Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review |
| title_short | Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review |
| title_sort | synthesis and pharmacological significance of isoxazoline derivatives a mini review |
| topic | Heterocyclic compounds, Isoxazoline, Biological activities, Anticancer activity, Antioxidant activity. |
| url | https://acadscij.uodiyala.edu.iq/index.php/Home/article/view/62 |
| work_keys_str_mv | AT mohammedalwan synthesisandpharmacologicalsignificanceofisoxazolinederivativesaminireview |