In Silico Prediction of Alkaline Phosphatase Interaction with the Natural Inhibitory 5-Azaindoles Guitarrin C and D

The natural 5-azaindoles, marine sponge guitarrin C and D, were observed to exert inhibitory activity against a highly active alkaline phosphatase (ALP) CmAP of the PhoA family from the marine bacterium <i>Cobetia amphilecti</i>, with IC<sub>50</sub> values of 8.5 and 110 µM,...

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Bibliographic Details
Main Authors: Aleksandra Seitkalieva, Yulia Noskova, Marina Isaeva, Alla Guzii, Tatyana N. Makarieva, Sergey Fedorov, Larissa Balabanova
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/29/23/5701
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