Silencing of CircTRIM25/miR-138-5p/CREB1 axis promotes chondrogenesis in osteoarthritis

Silencing of CircTRIM25/miR-138-5p/CREB1 axis promotes chondrogenesis in osteoarthritis

Background Dysregulated circular RNAs (circRNAs) are involved in osteoarthritis (OA) progression.Objective We aimed to explore the effect of hsa_circ_0044719 (circTRIM25) on the ferroptosis of chondrocytes.Methods Chondrocytes were treated with interleukin (IL)-1β to generate cell model. Cellular be...

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Bibliographic Details
Main Authors: Chunlei He, Zhaogan Zeng, Yadong Yang, Shanshan Ye, Qiang Wu, Xunzhi Liu, Chenghong Liu, Wanhui Zeng, Sheng Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autoimmunity
Subjects:
Osteoarthritis
circTRIM25
ferroptosis
miR-138a-5p
cartilage regeneration
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2024.2361749
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