Fatigue in children and adolescents with inflammatory bowel disease: a cross-sectional study
BackgroundIn recent years, there has been an observed increase in the global diagnosis rate of inflammatory bowel disease among children and adolescents. In inactive disease states, fatigue has emerged as the most debilitating symptom, while in active disease states, it ranks second. However, there...
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2024.1519779/full |
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| author | Yahui Zuo Yahui Zuo Jinjin Cao Yuanyuan Wang Yuanyuan Wang Wenqian Cai Wenqian Cai Wenqian Cai Mei Li |
| author_facet | Yahui Zuo Yahui Zuo Jinjin Cao Yuanyuan Wang Yuanyuan Wang Wenqian Cai Wenqian Cai Wenqian Cai Mei Li |
| author_sort | Yahui Zuo |
| collection | DOAJ |
| description | BackgroundIn recent years, there has been an observed increase in the global diagnosis rate of inflammatory bowel disease among children and adolescents. In inactive disease states, fatigue has emerged as the most debilitating symptom, while in active disease states, it ranks second. However, there remains a notable lack of understanding regarding fatigue in pediatric inflammatory bowel disease patients. Consequently, this study sought to investigate the prevalence and status of fatigue in a cohort of pediatric inflammatory bowel disease patients in China.MethodsA cross-sectional, questionnaire-based survey was conducted. The researchers recruited 110 patients with inflammatory bowel disease using the convenient sampling method between 1 September 2021 until 31 November 2022 in Department of Gastroenterology of Children's Hospital of Nanjing Medical University. Fatigue was assessed using the Multidimensional Fatigue Scale, while potential factors associated with fatigue were analyzed through univariate and multiple regression analyses.ResultsThe study found that the total score of fatigue in children with inflammatory bowel disease was 62.22 ± 20.55. The univariate analysis revealed significant differences in the degree of fatigue across regions, ages, disease severities, corticosteroid use, and biological agent use. Furthermore, the multiple regression analysis indicated a significant difference in BMI (p < 0.05).ConclusionsFatigue is a multidimensional symptom that affects a majority of pediatric inflammatory bowel disease patients. Factors such as patient region, age, disease severity, BMI, and drug use are significantly associated with fatigue. Healthcare providers should prioritize the assessment of fatigue symptoms in these patients. Following the initial assessment, targeted interventions should be implemented to alleviate and improve these symptoms. |
| format | Article |
| id | doaj-art-2f1cf9a6b65f4e7b90749657a10f4110 |
| institution | OA Journals |
| issn | 2296-2360 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-2f1cf9a6b65f4e7b90749657a10f41102025-08-20T01:58:08ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602024-12-011210.3389/fped.2024.15197791519779Fatigue in children and adolescents with inflammatory bowel disease: a cross-sectional studyYahui Zuo0Yahui Zuo1Jinjin Cao2Yuanyuan Wang3Yuanyuan Wang4Wenqian Cai5Wenqian Cai6Wenqian Cai7Mei Li8Department of Nursing, Children’s Hospital of Nanjing Medical University, Nanjing, ChinaSchool of Nursing, Nanjing Medical University, Nanjing, ChinaDepartment of Nursing, Nanjing BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Nursing, Children’s Hospital of Nanjing Medical University, Nanjing, ChinaSchool of Pediatrics, Nanjing Medical University, Nanjing, ChinaDepartment of Nursing, Children’s Hospital of Nanjing Medical University, Nanjing, ChinaSchool of Pediatrics, Nanjing Medical University, Nanjing, ChinaDepartment of Intensive Care Unit, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ChinaDepartment of Nursing, Children’s Hospital of Nanjing Medical University, Nanjing, ChinaBackgroundIn recent years, there has been an observed increase in the global diagnosis rate of inflammatory bowel disease among children and adolescents. In inactive disease states, fatigue has emerged as the most debilitating symptom, while in active disease states, it ranks second. However, there remains a notable lack of understanding regarding fatigue in pediatric inflammatory bowel disease patients. Consequently, this study sought to investigate the prevalence and status of fatigue in a cohort of pediatric inflammatory bowel disease patients in China.MethodsA cross-sectional, questionnaire-based survey was conducted. The researchers recruited 110 patients with inflammatory bowel disease using the convenient sampling method between 1 September 2021 until 31 November 2022 in Department of Gastroenterology of Children's Hospital of Nanjing Medical University. Fatigue was assessed using the Multidimensional Fatigue Scale, while potential factors associated with fatigue were analyzed through univariate and multiple regression analyses.ResultsThe study found that the total score of fatigue in children with inflammatory bowel disease was 62.22 ± 20.55. The univariate analysis revealed significant differences in the degree of fatigue across regions, ages, disease severities, corticosteroid use, and biological agent use. Furthermore, the multiple regression analysis indicated a significant difference in BMI (p < 0.05).ConclusionsFatigue is a multidimensional symptom that affects a majority of pediatric inflammatory bowel disease patients. Factors such as patient region, age, disease severity, BMI, and drug use are significantly associated with fatigue. Healthcare providers should prioritize the assessment of fatigue symptoms in these patients. Following the initial assessment, targeted interventions should be implemented to alleviate and improve these symptoms.https://www.frontiersin.org/articles/10.3389/fped.2024.1519779/fulladolescentschildrenfatigueinflammatory bowel diseaseinfluencing factors |
| spellingShingle | Yahui Zuo Yahui Zuo Jinjin Cao Yuanyuan Wang Yuanyuan Wang Wenqian Cai Wenqian Cai Wenqian Cai Mei Li Fatigue in children and adolescents with inflammatory bowel disease: a cross-sectional study Frontiers in Pediatrics adolescents children fatigue inflammatory bowel disease influencing factors |
| title | Fatigue in children and adolescents with inflammatory bowel disease: a cross-sectional study |
| title_full | Fatigue in children and adolescents with inflammatory bowel disease: a cross-sectional study |
| title_fullStr | Fatigue in children and adolescents with inflammatory bowel disease: a cross-sectional study |
| title_full_unstemmed | Fatigue in children and adolescents with inflammatory bowel disease: a cross-sectional study |
| title_short | Fatigue in children and adolescents with inflammatory bowel disease: a cross-sectional study |
| title_sort | fatigue in children and adolescents with inflammatory bowel disease a cross sectional study |
| topic | adolescents children fatigue inflammatory bowel disease influencing factors |
| url | https://www.frontiersin.org/articles/10.3389/fped.2024.1519779/full |
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