Clinical analysis of atrial fibrillation in pregnant women
Objective: To analyze the clinical characteristics and risk factors for the major adverse cardiovascular events (MACEs) of atrial fibrillation (AF) in pregnant women. Materials and Methods: A retrospective analysis was performed on 35 pregnant women with AF, who were treated at Beijing Anzhen Hospit...
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| Format: | Article |
| Language: | English |
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IMR Press
2020-04-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
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| Online Access: | https://www.imrpress.com/journal/CEOG/47/2/10.31083/j.ceog.2020.02.5014 |
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| author | H. F. Zhang J. Zhang D. Yang S. N. Li |
| author_facet | H. F. Zhang J. Zhang D. Yang S. N. Li |
| author_sort | H. F. Zhang |
| collection | DOAJ |
| description | Objective: To analyze the clinical characteristics and risk factors for the major adverse cardiovascular events (MACEs) of atrial fibrillation (AF) in pregnant women. Materials and Methods: A retrospective analysis was performed on 35 pregnant women with AF, who were treated at Beijing Anzhen Hospital, Capital Medical University, from January 2004 to May 2017. All pregnancies were recorded. Chi-squared test analysis was performed to determine the correlation between clinical factors and MACEs. Results: There were 11 cases of MACEs (31.4%), including 10 cases of heart failure (HF) and 1 case of cerebral infarction. We found 7 clinical factors with a clear correlation with the occurrence of MACEs during pregnancy: a medical history of heart operation (P = 0.0011) and AF before pregnancy (P = 0.0281), New York Heart Association (NYHA) class (P < 0.0001), a left ventricular ejection fraction (LVEF) ≤ 50% (P = 0.0055), and a delivery time < 37 weeks (P = 0.0037). The AF subtype and delivery mode have no correlation with MACEs. Conclusion: AF in pregnant women is dangerous for pregnancy and delivery, multi-disciplinary management of obstetricians, cardiologists, and neonatologists are crucial for these patients throughout pregnancy. |
| format | Article |
| id | doaj-art-2f1c1d91b76b4dc3a38a6870e520e6cb |
| institution | OA Journals |
| issn | 0390-6663 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj-art-2f1c1d91b76b4dc3a38a6870e520e6cb2025-08-20T02:08:11ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632020-04-0147217417810.31083/j.ceog.2020.02.5014S0390-6663(20)00229-8Clinical analysis of atrial fibrillation in pregnant womenH. F. Zhang0J. Zhang1D. Yang2S. N. Li3Obstetrics and Gynecology Medical Centre of Severe Cardiovascular Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. ChinaObstetrics and Gynecology Medical Centre of Severe Cardiovascular Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. ChinaObstetrics and Gynecology Medical Centre of Severe Cardiovascular Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. ChinaDepartment of Cardiology, Beijing Anzhen Hospital, Beijing 100029, P.R. ChinaObjective: To analyze the clinical characteristics and risk factors for the major adverse cardiovascular events (MACEs) of atrial fibrillation (AF) in pregnant women. Materials and Methods: A retrospective analysis was performed on 35 pregnant women with AF, who were treated at Beijing Anzhen Hospital, Capital Medical University, from January 2004 to May 2017. All pregnancies were recorded. Chi-squared test analysis was performed to determine the correlation between clinical factors and MACEs. Results: There were 11 cases of MACEs (31.4%), including 10 cases of heart failure (HF) and 1 case of cerebral infarction. We found 7 clinical factors with a clear correlation with the occurrence of MACEs during pregnancy: a medical history of heart operation (P = 0.0011) and AF before pregnancy (P = 0.0281), New York Heart Association (NYHA) class (P < 0.0001), a left ventricular ejection fraction (LVEF) ≤ 50% (P = 0.0055), and a delivery time < 37 weeks (P = 0.0037). The AF subtype and delivery mode have no correlation with MACEs. Conclusion: AF in pregnant women is dangerous for pregnancy and delivery, multi-disciplinary management of obstetricians, cardiologists, and neonatologists are crucial for these patients throughout pregnancy.https://www.imrpress.com/journal/CEOG/47/2/10.31083/j.ceog.2020.02.5014atrial fibrillationpregnancyclinical factorsmaces |
| spellingShingle | H. F. Zhang J. Zhang D. Yang S. N. Li Clinical analysis of atrial fibrillation in pregnant women Clinical and Experimental Obstetrics & Gynecology atrial fibrillation pregnancy clinical factors maces |
| title | Clinical analysis of atrial fibrillation in pregnant women |
| title_full | Clinical analysis of atrial fibrillation in pregnant women |
| title_fullStr | Clinical analysis of atrial fibrillation in pregnant women |
| title_full_unstemmed | Clinical analysis of atrial fibrillation in pregnant women |
| title_short | Clinical analysis of atrial fibrillation in pregnant women |
| title_sort | clinical analysis of atrial fibrillation in pregnant women |
| topic | atrial fibrillation pregnancy clinical factors maces |
| url | https://www.imrpress.com/journal/CEOG/47/2/10.31083/j.ceog.2020.02.5014 |
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