Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer
A woman in her 60s presented with a recurrent lymph node metastasis from a papillary thyroid carcinoma in the right parapharyngeal space. She had already undergone total thyroidectomy, five resections for cervical lymph node metastases, and right carotid rebuilding. Surgical resection of the current...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2017/7956726 |
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| author | Joji Kawabe Shigeaki Higashiyama Mitsuharu Sougawa Atsushi Yoshida Kohei Kotani Susumu Shiomi |
| author_facet | Joji Kawabe Shigeaki Higashiyama Mitsuharu Sougawa Atsushi Yoshida Kohei Kotani Susumu Shiomi |
| author_sort | Joji Kawabe |
| collection | DOAJ |
| description | A woman in her 60s presented with a recurrent lymph node metastasis from a papillary thyroid carcinoma in the right parapharyngeal space. She had already undergone total thyroidectomy, five resections for cervical lymph node metastases, and right carotid rebuilding. Surgical resection of the current metastasis was impossible. 131I-radioiodine therapy (RIT) with 3.7 GBq 131I was not effective; therefore, stereotactic radiation therapy (SRT) using a CyberKnife radiotherapy system was scheduled. The prescription dose was 21 Gy, and a dose covering 95% of the planning target volume (PTV) in three fractions was administered. The PTV was 4,790 mm3. Follow-up magnetic resonance imaging conducted 3 and 12 months after the SRT demonstrated a remarkable and gradual reduction of the recurrent lymph node metastasis in the right parapharyngeal space and no evidence of recurrence. For multidisciplinary therapy of unresectable and/or RIT unresponsive locoregional lymph node metastases and recurrences of DTC, SRT using the CyberKnife system should be considered. |
| format | Article |
| id | doaj-art-2f12e0ec797646528e1d99836c04d7cb |
| institution | DOAJ |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-2f12e0ec797646528e1d99836c04d7cb2025-08-20T03:18:43ZengWileyCase Reports in Endocrinology2090-65012090-651X2017-01-01201710.1155/2017/79567267956726Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid CancerJoji Kawabe0Shigeaki Higashiyama1Mitsuharu Sougawa2Atsushi Yoshida3Kohei Kotani4Susumu Shiomi5Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanDepartment of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanCyberKnife Center, Osaka Medical College Mishima-Minami Hospital, Osaka, JapanDepartment of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanDepartment of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanDepartment of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanA woman in her 60s presented with a recurrent lymph node metastasis from a papillary thyroid carcinoma in the right parapharyngeal space. She had already undergone total thyroidectomy, five resections for cervical lymph node metastases, and right carotid rebuilding. Surgical resection of the current metastasis was impossible. 131I-radioiodine therapy (RIT) with 3.7 GBq 131I was not effective; therefore, stereotactic radiation therapy (SRT) using a CyberKnife radiotherapy system was scheduled. The prescription dose was 21 Gy, and a dose covering 95% of the planning target volume (PTV) in three fractions was administered. The PTV was 4,790 mm3. Follow-up magnetic resonance imaging conducted 3 and 12 months after the SRT demonstrated a remarkable and gradual reduction of the recurrent lymph node metastasis in the right parapharyngeal space and no evidence of recurrence. For multidisciplinary therapy of unresectable and/or RIT unresponsive locoregional lymph node metastases and recurrences of DTC, SRT using the CyberKnife system should be considered.http://dx.doi.org/10.1155/2017/7956726 |
| spellingShingle | Joji Kawabe Shigeaki Higashiyama Mitsuharu Sougawa Atsushi Yoshida Kohei Kotani Susumu Shiomi Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer Case Reports in Endocrinology |
| title | Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer |
| title_full | Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer |
| title_fullStr | Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer |
| title_full_unstemmed | Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer |
| title_short | Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer |
| title_sort | usefulness of stereotactic radiotherapy using cyberknife for recurrent lymph node metastasis of differentiated thyroid cancer |
| url | http://dx.doi.org/10.1155/2017/7956726 |
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