Mixed Epithelial and Stromal Tumor of the Kidney in a Patient With Mental Retardation: A Case Report

ABSTRACT Introduction Mixed epithelial and stromal tumors are rare renal neoplasms. Case Presentation A 55‐year‐old woman with mental retardation presented with a giant renal tumor with abdominal pain. After a renal biopsy with a definitive diagnosis, an open total nephrectomy was performed. There w...

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Main Authors: Kazuki Sato, Kotaro Hirai, Yumiko Yokomizo, Azumi Fujioka, Yuki Ito, Sawako Chiba, Junichi Murayama
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:IJU Case Reports
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Online Access:https://doi.org/10.1002/iju5.70043
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author Kazuki Sato
Kotaro Hirai
Yumiko Yokomizo
Azumi Fujioka
Yuki Ito
Sawako Chiba
Junichi Murayama
author_facet Kazuki Sato
Kotaro Hirai
Yumiko Yokomizo
Azumi Fujioka
Yuki Ito
Sawako Chiba
Junichi Murayama
author_sort Kazuki Sato
collection DOAJ
description ABSTRACT Introduction Mixed epithelial and stromal tumors are rare renal neoplasms. Case Presentation A 55‐year‐old woman with mental retardation presented with a giant renal tumor with abdominal pain. After a renal biopsy with a definitive diagnosis, an open total nephrectomy was performed. There was no recurrence for the following year. Clinical Discussion Since a definitive diagnosis of MEST cannot be made through imaging alone, surgery is the preferred diagnostic treatment. To our knowledge, renal biopsy has only been reported in three cases. There are only two reports of nonsurgical treatment of benign MEST and no reports of malignant transformation or exacerbation. Conclusion If the biopsy findings are suggestive of a benign tumor, follow‐up is an option. We look forward to reporting the long‐term outcomes of the conservative management of MEST.
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series IJU Case Reports
spelling doaj-art-2f0d88273fd844048e7388a618a2dcca2025-08-20T02:38:09ZengWileyIJU Case Reports2577-171X2025-07-018437337610.1002/iju5.70043Mixed Epithelial and Stromal Tumor of the Kidney in a Patient With Mental Retardation: A Case ReportKazuki Sato0Kotaro Hirai1Yumiko Yokomizo2Azumi Fujioka3Yuki Ito4Sawako Chiba5Junichi Murayama6Department of Urology Yokohama Medical Center Yokohama Kanagawa JapanDepartment of Urology Yokohama Medical Center Yokohama Kanagawa JapanDepartment of Urology Yokohama Medical Center Yokohama Kanagawa JapanDepartment of Urology Yokohama Medical Center Yokohama Kanagawa JapanDepartment of Urology Yokohama Medical Center Yokohama Kanagawa JapanDepartment of Clinical Laboratories Yokohama Medical Center Yokohama Kanagawa JapanGeneral Medicine Department Yokohama Medical Center Yokohama Kanagawa JapanABSTRACT Introduction Mixed epithelial and stromal tumors are rare renal neoplasms. Case Presentation A 55‐year‐old woman with mental retardation presented with a giant renal tumor with abdominal pain. After a renal biopsy with a definitive diagnosis, an open total nephrectomy was performed. There was no recurrence for the following year. Clinical Discussion Since a definitive diagnosis of MEST cannot be made through imaging alone, surgery is the preferred diagnostic treatment. To our knowledge, renal biopsy has only been reported in three cases. There are only two reports of nonsurgical treatment of benign MEST and no reports of malignant transformation or exacerbation. Conclusion If the biopsy findings are suggestive of a benign tumor, follow‐up is an option. We look forward to reporting the long‐term outcomes of the conservative management of MEST.https://doi.org/10.1002/iju5.70043kidneymental retardationmixed epithelial and stromal tumorsrenal biopsy
spellingShingle Kazuki Sato
Kotaro Hirai
Yumiko Yokomizo
Azumi Fujioka
Yuki Ito
Sawako Chiba
Junichi Murayama
Mixed Epithelial and Stromal Tumor of the Kidney in a Patient With Mental Retardation: A Case Report
IJU Case Reports
kidney
mental retardation
mixed epithelial and stromal tumors
renal biopsy
title Mixed Epithelial and Stromal Tumor of the Kidney in a Patient With Mental Retardation: A Case Report
title_full Mixed Epithelial and Stromal Tumor of the Kidney in a Patient With Mental Retardation: A Case Report
title_fullStr Mixed Epithelial and Stromal Tumor of the Kidney in a Patient With Mental Retardation: A Case Report
title_full_unstemmed Mixed Epithelial and Stromal Tumor of the Kidney in a Patient With Mental Retardation: A Case Report
title_short Mixed Epithelial and Stromal Tumor of the Kidney in a Patient With Mental Retardation: A Case Report
title_sort mixed epithelial and stromal tumor of the kidney in a patient with mental retardation a case report
topic kidney
mental retardation
mixed epithelial and stromal tumors
renal biopsy
url https://doi.org/10.1002/iju5.70043
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