Study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it. (morphological and histological study)

The present study was designed to identify the effect of obesity on liver and kidneys rats fetuses Rattus norvegicus and the ability of grape seeds oil to treat these effects. The present study used 12 female rat which divided randomly into three groups (each group containing four female) the fi...

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Main Authors: Rashid Khamees Shaaban, Aziz Khalid Hameed
Format: Article
Language:English
Published: Tikrit University 2023-01-01
Series:Tikrit Journal of Pure Science
Subjects:
Online Access:https://tjpsj.org/index.php/tjps/article/view/726
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author Rashid Khamees Shaaban
Aziz Khalid Hameed
author_facet Rashid Khamees Shaaban
Aziz Khalid Hameed
author_sort Rashid Khamees Shaaban
collection DOAJ
description The present study was designed to identify the effect of obesity on liver and kidneys rats fetuses Rattus norvegicus and the ability of grape seeds oil to treat these effects. The present study used 12 female rat which divided randomly into three groups (each group containing four female) the first group was control group administrated only normal diet and water, the second group was fed a high fat diet for three months, the third groups fed a high fat diet for three months and treated with grape seed oil at a dose of 0.1 ml/ kg body weight. The results showed the effect of a high fat diet lead to inducing morphological changes in fetuses included decrease in the numbers and sizes of fetuses in the horns of uterus with shortness in the limbs. The histological lesions included necrosis, degenerative changes, in liver tissue with increased in sinusoids diameter. About kidneys, the lesions included desquamation of epithelium of some proximal convoluted tubules with damage of some of its, also damage glomeruli. After the treatment with grape seeds oil observed most of the embryos appeared normal in size and number without any lesions in the liver and kidney tissue of embryos.
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institution Kabale University
issn 1813-1662
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publishDate 2023-01-01
publisher Tikrit University
record_format Article
series Tikrit Journal of Pure Science
spelling doaj-art-2ef96b077cfb4283b717f2530e93a8752025-08-20T03:29:14ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262023-01-0122410.25130/tjps.v22i4.726Study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it. (morphological and histological study)Rashid Khamees ShaabanAziz Khalid Hameed The present study was designed to identify the effect of obesity on liver and kidneys rats fetuses Rattus norvegicus and the ability of grape seeds oil to treat these effects. The present study used 12 female rat which divided randomly into three groups (each group containing four female) the first group was control group administrated only normal diet and water, the second group was fed a high fat diet for three months, the third groups fed a high fat diet for three months and treated with grape seed oil at a dose of 0.1 ml/ kg body weight. The results showed the effect of a high fat diet lead to inducing morphological changes in fetuses included decrease in the numbers and sizes of fetuses in the horns of uterus with shortness in the limbs. The histological lesions included necrosis, degenerative changes, in liver tissue with increased in sinusoids diameter. About kidneys, the lesions included desquamation of epithelium of some proximal convoluted tubules with damage of some of its, also damage glomeruli. After the treatment with grape seeds oil observed most of the embryos appeared normal in size and number without any lesions in the liver and kidney tissue of embryos. https://tjpsj.org/index.php/tjps/article/view/726liverkidneywhite ratsgrape seed oilmorphological and histological study
spellingShingle Rashid Khamees Shaaban
Aziz Khalid Hameed
Study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it. (morphological and histological study)
Tikrit Journal of Pure Science
liver
kidney
white rats
grape seed oil
morphological and histological study
title Study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it. (morphological and histological study)
title_full Study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it. (morphological and histological study)
title_fullStr Study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it. (morphological and histological study)
title_full_unstemmed Study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it. (morphological and histological study)
title_short Study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it. (morphological and histological study)
title_sort study the effect of obesity on the liver and kidney of the white rats embryos followed by using of grape seed oil to treat it morphological and histological study
topic liver
kidney
white rats
grape seed oil
morphological and histological study
url https://tjpsj.org/index.php/tjps/article/view/726
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AT azizkhalidhameed studytheeffectofobesityontheliverandkidneyofthewhiteratsembryosfollowedbyusingofgrapeseedoiltotreatitmorphologicalandhistologicalstudy