Experience in the use of vaccine Gam-Kovid-Vak-M for the prevention of COVID-19 in children
The goal is to evaluate the tolerability and effectiveness of the domestic vector vaccine Gam-Covid-Vak-M in children aged 12—17 years, adherence to vaccination of adolescents and parents to improve work on the prevention of COVID-19. Materials and methods. A retrospective analysis of the medical re...
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| Format: | Article |
| Language: | Russian |
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LLC "Diagnostics and Vaccines"
2023-10-01
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| Series: | Детские инфекции (Москва) |
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| Online Access: | https://detinf.elpub.ru/jour/article/view/866 |
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| author | T. M. Chernova D. O. Ivanov V. N. Timchenko S. M. Kharit M. E. Balakina Yu. K. Miroshnikova E. V. Barakina E. B. Pavlova A. V. Morozova N. A. Myskina I. Yu. Bazunova A. A. Zherebtsov |
| author_facet | T. M. Chernova D. O. Ivanov V. N. Timchenko S. M. Kharit M. E. Balakina Yu. K. Miroshnikova E. V. Barakina E. B. Pavlova A. V. Morozova N. A. Myskina I. Yu. Bazunova A. A. Zherebtsov |
| author_sort | T. M. Chernova |
| collection | DOAJ |
| description | The goal is to evaluate the tolerability and effectiveness of the domestic vector vaccine Gam-Covid-Vak-M in children aged 12—17 years, adherence to vaccination of adolescents and parents to improve work on the prevention of COVID-19. Materials and methods. A retrospective analysis of the medical records of 115 children aged 12—17 years who were vaccinated in 2022 with the Gam-COVID-Vac-M vaccine in two children's polyclinics in St. Petersburg was carried out. Additional information was collected through telephone interviews. A cross-sectional anonymous online survey of adolescents aged 15—17 was also conducted to study awareness of COVID-19 and adherence to vaccination. Results. Only 23.5% of those vaccinated were at risk for severe and complicated COVID-19. Parents showed low adherence to vaccination against COVID-19 — 71.3% vaccinated themselves and 73.1% considered it necessary to protect the child. Only in 14.1% of cases, a teenager aged 15—17 made the decision to be vaccinated. According to 76.9% of adolescents, COVID-19 is a dangerous disease, while 55.6% consider vaccination unnecessary, mainly due to ineffective protection and the possibility of complications. Nevertheless, side effects after the first and second components of Gam-COVID-Vac-M were observed in 24.3% and 24.2%, respectively, which is 4 times less than with foreign vaccines. Systemic and local reactions were observed on days 1—2 after immunization. All manifestations were mild or moderate and resolved within 1—2 days on average. Serious adverse events were not registered. The effectiveness of the vaccine was 97.4%. Conclusion. Preliminary results indicate good tolerance and efficacy of the domestic vaccine Gam-COVID-Vac-M. |
| format | Article |
| id | doaj-art-2ef10121cbab43dbaa2867a71b5b3542 |
| institution | DOAJ |
| issn | 2072-8107 |
| language | Russian |
| publishDate | 2023-10-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj-art-2ef10121cbab43dbaa2867a71b5b35422025-08-20T02:46:33ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072023-10-01223333810.22627/2072-8107-2023-22-3-33-38624Experience in the use of vaccine Gam-Kovid-Vak-M for the prevention of COVID-19 in childrenT. M. Chernova0D. O. Ivanov1V. N. Timchenko2S. M. Kharit3M. E. Balakina4Yu. K. Miroshnikova5E. V. Barakina6E. B. Pavlova7A. V. Morozova8N. A. Myskina9I. Yu. Bazunova10A. A. Zherebtsov11St. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical University; Children’s Scientific and Clinical Center for Infectious Diseases of the Federal Medical and Biological AgencySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversityChildren’s polyclinic department № 41Children’s polyclinic department № 41City Polyclinic No. 27City Polyclinic No. 27The goal is to evaluate the tolerability and effectiveness of the domestic vector vaccine Gam-Covid-Vak-M in children aged 12—17 years, adherence to vaccination of adolescents and parents to improve work on the prevention of COVID-19. Materials and methods. A retrospective analysis of the medical records of 115 children aged 12—17 years who were vaccinated in 2022 with the Gam-COVID-Vac-M vaccine in two children's polyclinics in St. Petersburg was carried out. Additional information was collected through telephone interviews. A cross-sectional anonymous online survey of adolescents aged 15—17 was also conducted to study awareness of COVID-19 and adherence to vaccination. Results. Only 23.5% of those vaccinated were at risk for severe and complicated COVID-19. Parents showed low adherence to vaccination against COVID-19 — 71.3% vaccinated themselves and 73.1% considered it necessary to protect the child. Only in 14.1% of cases, a teenager aged 15—17 made the decision to be vaccinated. According to 76.9% of adolescents, COVID-19 is a dangerous disease, while 55.6% consider vaccination unnecessary, mainly due to ineffective protection and the possibility of complications. Nevertheless, side effects after the first and second components of Gam-COVID-Vac-M were observed in 24.3% and 24.2%, respectively, which is 4 times less than with foreign vaccines. Systemic and local reactions were observed on days 1—2 after immunization. All manifestations were mild or moderate and resolved within 1—2 days on average. Serious adverse events were not registered. The effectiveness of the vaccine was 97.4%. Conclusion. Preliminary results indicate good tolerance and efficacy of the domestic vaccine Gam-COVID-Vac-M.https://detinf.elpub.ru/jour/article/view/866сovid-19childrengam-covid-vak-mside effectsadherence to vaccination |
| spellingShingle | T. M. Chernova D. O. Ivanov V. N. Timchenko S. M. Kharit M. E. Balakina Yu. K. Miroshnikova E. V. Barakina E. B. Pavlova A. V. Morozova N. A. Myskina I. Yu. Bazunova A. A. Zherebtsov Experience in the use of vaccine Gam-Kovid-Vak-M for the prevention of COVID-19 in children Детские инфекции (Москва) сovid-19 children gam-covid-vak-m side effects adherence to vaccination |
| title | Experience in the use of vaccine Gam-Kovid-Vak-M for the prevention of COVID-19 in children |
| title_full | Experience in the use of vaccine Gam-Kovid-Vak-M for the prevention of COVID-19 in children |
| title_fullStr | Experience in the use of vaccine Gam-Kovid-Vak-M for the prevention of COVID-19 in children |
| title_full_unstemmed | Experience in the use of vaccine Gam-Kovid-Vak-M for the prevention of COVID-19 in children |
| title_short | Experience in the use of vaccine Gam-Kovid-Vak-M for the prevention of COVID-19 in children |
| title_sort | experience in the use of vaccine gam kovid vak m for the prevention of covid 19 in children |
| topic | сovid-19 children gam-covid-vak-m side effects adherence to vaccination |
| url | https://detinf.elpub.ru/jour/article/view/866 |
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