A decade of antimicrobial resistance trends in Pseudomonas aeruginosa: insights from a tertiary care hospital in Saudi Arabia (2013–2022)
BackgroundPseudomonas aeruginosa (PA) is a significant cause of nosocomial infections, and increasing antimicrobial resistance complicates management.ObjectivesTo characterize antimicrobial susceptibility trends, we conducted a retrospective study of PA clinical isolates over 10 years (2013–2022) at...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
|
| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1617522/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | BackgroundPseudomonas aeruginosa (PA) is a significant cause of nosocomial infections, and increasing antimicrobial resistance complicates management.ObjectivesTo characterize antimicrobial susceptibility trends, we conducted a retrospective study of PA clinical isolates over 10 years (2013–2022) at a tertiary care hospital in Saudi Arabia.ResultsA total of 2,490 PA isolates were analyzed (1,452 from general wards and 1,038 from ICUs). Carbapenem resistance was observed in 40% of isolates; 37.5% were multidrug-resistant (MDR), 5.3% were extensively drug-resistant (XDR), and 3.5% met the criteria for difficult-to-treat resistance (DTR).ConclusionThis study provides an overview of PA resistance pattern trends in Saudi Arabia and emphasizes the importance of establishing an antimicrobial stewardship program. |
|---|---|
| ISSN: | 1664-302X |