Optimization of a Sonotrode Extraction Method and New Insight of Phenolic Composition of <i>Fucus vesiculosus</i>
The optimization of bioactive compound extraction from <i>Fucus vesiculosus</i> using ultrasound-assisted extraction (UAE) via sonotrode was investigated to maximize phenolic recovery and antioxidant activity while promoting a sustainable process. Optimal conditions (40% <i>v</i...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1660-3397/23/1/40 |
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| Summary: | The optimization of bioactive compound extraction from <i>Fucus vesiculosus</i> using ultrasound-assisted extraction (UAE) via sonotrode was investigated to maximize phenolic recovery and antioxidant activity while promoting a sustainable process. Optimal conditions (40% <i>v</i>/<i>v</i> ethanol in water, 38 min, 36% amplitude) were selected to maximize phenolic recovery while considering environmental and energy sustainability by optimizing extraction efficiency and minimizing solvent and energy usage. HPLC-ESI-QTOF-MS analysis tentatively identified 25 phenolic compounds, including sulfated phenolic acids, phlorotannins, flavonoids, and halophenols, with some reported for the first time in <i>F. vesiculosus</i>, underscoring the complexity of this alga’s metabolome. The antioxidant activity of the optimized extract was evaluated through FRAP (143.7 µmol TE/g), DPPH (EC<sub>50</sub> 105.6 µg/mL), and TEAC (189.1 µmol Trolox/g) assays. The optimized process highlights <i>F. vesiculosus</i> as a valuable source of natural antioxidants, with potential applications in biotechnology, cosmetics, and food industries. |
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| ISSN: | 1660-3397 |