Classification of diabetes. World Health Organization 2019. What’s new?

The review focuses on the new WHO classification published in 2019. Unlike the previous classification, this classification does not recognize subtypes of T1DM and T2DM and offers new types of diabetes: “hybrid types of diabetes” and “unclassified diabetes”. This classification provides practical gu...

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Main Authors: Irina V. Kononenko, Olga M. Smirnova, Aleksandr Y. Mayorov, Marina V. Shestakova
Format: Article
Language:English
Published: Endocrinology Research Centre 2020-12-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/12405
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author Irina V. Kononenko
Olga M. Smirnova
Aleksandr Y. Mayorov
Marina V. Shestakova
author_facet Irina V. Kononenko
Olga M. Smirnova
Aleksandr Y. Mayorov
Marina V. Shestakova
author_sort Irina V. Kononenko
collection DOAJ
description The review focuses on the new WHO classification published in 2019. Unlike the previous classification, this classification does not recognize subtypes of T1DM and T2DM and offers new types of diabetes: “hybrid types of diabetes” and “unclassified diabetes”. This classification provides practical guidance to clinicians for assigning a type of diabetes to individuals and choose appropriate treatment (whether or not to start treatment with insulin), particularly at the time of diagnosis. This review presents the variety of forms of diabetes, the features of their clinical picture, and also emphasizes the importance of molecular genetic and immunological studies to identify types of diabetes and determine personalized therapy. The selection of “hybrid forms” of diabetes is due to the fact that the treatment of these types of diabetes has its own characteristics associated with the specific pathogenesis of diseases. However, it is obvious that further studies should relate to the study of the mechanisms of damage and decrease in the function of в-cells. Perhaps future classification systems and, as a consequence, personalized treatment will focus on various mechanisms of damage to β-cells.
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series Сахарный диабет
spelling doaj-art-2ee149cb621347f4a5240cfd954e3a2a2025-08-20T02:29:40ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782020-12-0123432933910.14341/DM1240510751Classification of diabetes. World Health Organization 2019. What’s new?Irina V. Kononenko0Olga M. Smirnova1Aleksandr Y. Mayorov2Marina V. Shestakova3Endocrinology Research CentreEndocrinology Research CentreEndocrinology Research CentreEndocrinology Research Centre; I.M. Sechenov First Moscow State Medical UniversityThe review focuses on the new WHO classification published in 2019. Unlike the previous classification, this classification does not recognize subtypes of T1DM and T2DM and offers new types of diabetes: “hybrid types of diabetes” and “unclassified diabetes”. This classification provides practical guidance to clinicians for assigning a type of diabetes to individuals and choose appropriate treatment (whether or not to start treatment with insulin), particularly at the time of diagnosis. This review presents the variety of forms of diabetes, the features of their clinical picture, and also emphasizes the importance of molecular genetic and immunological studies to identify types of diabetes and determine personalized therapy. The selection of “hybrid forms” of diabetes is due to the fact that the treatment of these types of diabetes has its own characteristics associated with the specific pathogenesis of diseases. However, it is obvious that further studies should relate to the study of the mechanisms of damage and decrease in the function of в-cells. Perhaps future classification systems and, as a consequence, personalized treatment will focus on various mechanisms of damage to β-cells.https://www.dia-endojournals.ru/jour/article/view/12405classificationdiabetes mellitus hybrid types of diabetesmolecular genetic studiesimmunological studies
spellingShingle Irina V. Kononenko
Olga M. Smirnova
Aleksandr Y. Mayorov
Marina V. Shestakova
Classification of diabetes. World Health Organization 2019. What’s new?
Сахарный диабет
classification
diabetes mellitus hybrid types of diabetes
molecular genetic studies
immunological studies
title Classification of diabetes. World Health Organization 2019. What’s new?
title_full Classification of diabetes. World Health Organization 2019. What’s new?
title_fullStr Classification of diabetes. World Health Organization 2019. What’s new?
title_full_unstemmed Classification of diabetes. World Health Organization 2019. What’s new?
title_short Classification of diabetes. World Health Organization 2019. What’s new?
title_sort classification of diabetes world health organization 2019 what s new
topic classification
diabetes mellitus hybrid types of diabetes
molecular genetic studies
immunological studies
url https://www.dia-endojournals.ru/jour/article/view/12405
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AT marinavshestakova classificationofdiabetesworldhealthorganization2019whatsnew