Prenatal and Obstetric Risk Factors for Development of Disabilities in Childhood
The main objective was to analyze prenatal and obstetric risk factors in relation to the development of disabilities. For that purpose, data on medication, i.e., use of benzodiazepines during pregnancy, gestational weeks, mode of delivery (vaginal or cesarean section), duration of delivery, and f...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2024-01-01
|
| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/482030 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849320548245438464 |
|---|---|
| author | Ksenija Romstein Dubravko Habek Tena Velki Maja Košuta Petrović |
| author_facet | Ksenija Romstein Dubravko Habek Tena Velki Maja Košuta Petrović |
| author_sort | Ksenija Romstein |
| collection | DOAJ |
| description | The main objective was to analyze prenatal and obstetric risk factors in relation
to the development of disabilities. For that purpose, data on medication, i.e., use of benzodiazepines
during pregnancy, gestational weeks, mode of delivery (vaginal or cesarean section), duration of
delivery, and fetal presentation were retrieved from medical records and semi-structured interviews
with mothers/legal guardians. Trained professionals clinically assessed the children’s developmental
status (N=107). Fisher exact test with post hoc analysis of standardized residuals showed that a
statistically significant number of children with multiple disabilities were born by cesarean section
(z=3.7, p<0.001), prematurely (z=4.8, p<0.001), and by mothers using benzodiazepines (z=2.6,
p<0.01). Children with autism spectrum disorders were more often delivered post-term (z=2.0,
p<0.05) by induced delivery (z=2.9, p<0.01). Children with developmental coordination disorder
were more often born post-term (z=2.2, p<0.05). As for the duration of delivery and fetal presentation,
there was no statistically significant correlation with developmental disabilities. There is
a cumulative risk of developmental disabilities rather than just a single risk factor. More interdisciplinary
and longitudinal research on developmental disabilities, including children’s educational
outcomes should be conducted. |
| format | Article |
| id | doaj-art-2ed8418fa4bf4cc59d5f67df3a4c587f |
| institution | Kabale University |
| issn | 0353-9466 1333-9451 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj-art-2ed8418fa4bf4cc59d5f67df3a4c587f2025-08-20T03:50:02ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512024-01-0163.3-467067610.20471/acc.2024.63.03-04.27Prenatal and Obstetric Risk Factors for Development of Disabilities in ChildhoodKsenija Romstein0Dubravko Habek1Tena Velki2Maja Košuta Petrović3Josip Juraj Strossmayer University of Osijek, Osijek Faculty of Education, Osijek, CroatiaUniversity Hospital “Merkur“; Catholic University of Croatia, School of Medicine, Zagreb, CroatiaJosip Juraj Strossmayer University of Osijek, Osijek Faculty of Education, Osijek, CroatiaOsijek University Hospital Center, Department of Obstetrics and Gynecology, Osijek, CroatiaThe main objective was to analyze prenatal and obstetric risk factors in relation to the development of disabilities. For that purpose, data on medication, i.e., use of benzodiazepines during pregnancy, gestational weeks, mode of delivery (vaginal or cesarean section), duration of delivery, and fetal presentation were retrieved from medical records and semi-structured interviews with mothers/legal guardians. Trained professionals clinically assessed the children’s developmental status (N=107). Fisher exact test with post hoc analysis of standardized residuals showed that a statistically significant number of children with multiple disabilities were born by cesarean section (z=3.7, p<0.001), prematurely (z=4.8, p<0.001), and by mothers using benzodiazepines (z=2.6, p<0.01). Children with autism spectrum disorders were more often delivered post-term (z=2.0, p<0.05) by induced delivery (z=2.9, p<0.01). Children with developmental coordination disorder were more often born post-term (z=2.2, p<0.05). As for the duration of delivery and fetal presentation, there was no statistically significant correlation with developmental disabilities. There is a cumulative risk of developmental disabilities rather than just a single risk factor. More interdisciplinary and longitudinal research on developmental disabilities, including children’s educational outcomes should be conducted.https://hrcak.srce.hr/file/482030CausalityDevelopmental disabilitiesParturitionPregnancyRisk factors |
| spellingShingle | Ksenija Romstein Dubravko Habek Tena Velki Maja Košuta Petrović Prenatal and Obstetric Risk Factors for Development of Disabilities in Childhood Acta Clinica Croatica Causality Developmental disabilities Parturition Pregnancy Risk factors |
| title | Prenatal and Obstetric Risk Factors for Development of Disabilities in Childhood |
| title_full | Prenatal and Obstetric Risk Factors for Development of Disabilities in Childhood |
| title_fullStr | Prenatal and Obstetric Risk Factors for Development of Disabilities in Childhood |
| title_full_unstemmed | Prenatal and Obstetric Risk Factors for Development of Disabilities in Childhood |
| title_short | Prenatal and Obstetric Risk Factors for Development of Disabilities in Childhood |
| title_sort | prenatal and obstetric risk factors for development of disabilities in childhood |
| topic | Causality Developmental disabilities Parturition Pregnancy Risk factors |
| url | https://hrcak.srce.hr/file/482030 |
| work_keys_str_mv | AT ksenijaromstein prenatalandobstetricriskfactorsfordevelopmentofdisabilitiesinchildhood AT dubravkohabek prenatalandobstetricriskfactorsfordevelopmentofdisabilitiesinchildhood AT tenavelki prenatalandobstetricriskfactorsfordevelopmentofdisabilitiesinchildhood AT majakosutapetrovic prenatalandobstetricriskfactorsfordevelopmentofdisabilitiesinchildhood |