Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased est...
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Wiley
2012-01-01
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Series: | Case Reports in Cardiology |
Online Access: | http://dx.doi.org/10.1155/2012/524508 |
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author | Alexander L. Pan David Fergusson Robert Hong Ramy A. Badawi |
author_facet | Alexander L. Pan David Fergusson Robert Hong Ramy A. Badawi |
author_sort | Alexander L. Pan |
collection | DOAJ |
description | Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases of spontaneous coronary dissection with topical hormonal replacement therapy. We describe a 53-year-old female who developed two spontaneous coronary dissections while on topical hormonal replacement therapy. The patient had no other risk factors for coronary dissection. After withdrawal from topical hormonal therapy, our patient has done well and has not had recurrent coronary artery dissections over a one-year follow-up period. The potential contributory role of topical hormonal therapy as a cause of spontaneous coronary dissection should be recognized. |
format | Article |
id | doaj-art-2ed02b34abff4716a9a6e9eba70128ae |
institution | Kabale University |
issn | 2090-6404 2090-6412 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Cardiology |
spelling | doaj-art-2ed02b34abff4716a9a6e9eba70128ae2025-02-03T06:12:14ZengWileyCase Reports in Cardiology2090-64042090-64122012-01-01201210.1155/2012/524508524508Spontaneous Coronary Artery Dissection following Topical Hormone Replacement TherapyAlexander L. Pan0David Fergusson1Robert Hong2Ramy A. Badawi3Division of Cardiology, The John A. Burns School of Medicine, University of Hawaii, Queens Medical Center, Honolulu, HI 96813, USADivision of Cardiology, The John A. Burns School of Medicine, University of Hawaii, Queens Medical Center, Honolulu, HI 96813, USADivision of Cardiology, The John A. Burns School of Medicine, University of Hawaii, Queens Medical Center, Honolulu, HI 96813, USADivision of Cardiology, The John A. Burns School of Medicine, University of Hawaii, Queens Medical Center, Honolulu, HI 96813, USASpontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases of spontaneous coronary dissection with topical hormonal replacement therapy. We describe a 53-year-old female who developed two spontaneous coronary dissections while on topical hormonal replacement therapy. The patient had no other risk factors for coronary dissection. After withdrawal from topical hormonal therapy, our patient has done well and has not had recurrent coronary artery dissections over a one-year follow-up period. The potential contributory role of topical hormonal therapy as a cause of spontaneous coronary dissection should be recognized.http://dx.doi.org/10.1155/2012/524508 |
spellingShingle | Alexander L. Pan David Fergusson Robert Hong Ramy A. Badawi Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy Case Reports in Cardiology |
title | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_full | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_fullStr | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_full_unstemmed | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_short | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_sort | spontaneous coronary artery dissection following topical hormone replacement therapy |
url | http://dx.doi.org/10.1155/2012/524508 |
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