ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination
We experienced a case of myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis after Moderna COVID-19 vaccination. An 82-year-old woman developed pyrexia and general malaise one month after her third booster vaccine, and the symptoms persisted. Blood testing revealed i...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-01-01
|
| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2023/4906876 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849699110436732928 |
|---|---|
| author | Shiko Gen Takanori Iwai Sayuri Ohnari Kanako Nobe Naofumi Ikeda |
| author_facet | Shiko Gen Takanori Iwai Sayuri Ohnari Kanako Nobe Naofumi Ikeda |
| author_sort | Shiko Gen |
| collection | DOAJ |
| description | We experienced a case of myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis after Moderna COVID-19 vaccination. An 82-year-old woman developed pyrexia and general malaise one month after her third booster vaccine, and the symptoms persisted. Blood testing revealed inflammation, a high level of MPO-ANCA, and microscopic hematuria. MPO-ANCA-associated vasculitis was diagnosed by renal biopsy. The symptoms improved with steroid therapy. Common adverse reactions to mRNA vaccines against COVID-19 include pyrexia and general malaise, but MPO-ANCA-associated vasculitis can also occur. If pyrexia, prolonged general malaise, urinary occult blood, or renal impairment is observed, the onset of MPO-ANCA-associated vasculitis should be considered. |
| format | Article |
| id | doaj-art-2ecf1531ae564b42b9b1c034129e714f |
| institution | DOAJ |
| issn | 2090-665X |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-2ecf1531ae564b42b9b1c034129e714f2025-08-20T03:18:42ZengWileyCase Reports in Nephrology2090-665X2023-01-01202310.1155/2023/4906876ANCA-Associated Vasculitis after Moderna COVID-19 VaccinationShiko Gen0Takanori Iwai1Sayuri Ohnari2Kanako Nobe3Naofumi Ikeda4Department of NephrologyDepartment of NephrologyDepartment of NephrologyDepartment of NephrologyDepartment of NephrologyWe experienced a case of myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis after Moderna COVID-19 vaccination. An 82-year-old woman developed pyrexia and general malaise one month after her third booster vaccine, and the symptoms persisted. Blood testing revealed inflammation, a high level of MPO-ANCA, and microscopic hematuria. MPO-ANCA-associated vasculitis was diagnosed by renal biopsy. The symptoms improved with steroid therapy. Common adverse reactions to mRNA vaccines against COVID-19 include pyrexia and general malaise, but MPO-ANCA-associated vasculitis can also occur. If pyrexia, prolonged general malaise, urinary occult blood, or renal impairment is observed, the onset of MPO-ANCA-associated vasculitis should be considered.http://dx.doi.org/10.1155/2023/4906876 |
| spellingShingle | Shiko Gen Takanori Iwai Sayuri Ohnari Kanako Nobe Naofumi Ikeda ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination Case Reports in Nephrology |
| title | ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination |
| title_full | ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination |
| title_fullStr | ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination |
| title_full_unstemmed | ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination |
| title_short | ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination |
| title_sort | anca associated vasculitis after moderna covid 19 vaccination |
| url | http://dx.doi.org/10.1155/2023/4906876 |
| work_keys_str_mv | AT shikogen ancaassociatedvasculitisaftermodernacovid19vaccination AT takanoriiwai ancaassociatedvasculitisaftermodernacovid19vaccination AT sayuriohnari ancaassociatedvasculitisaftermodernacovid19vaccination AT kanakonobe ancaassociatedvasculitisaftermodernacovid19vaccination AT naofumiikeda ancaassociatedvasculitisaftermodernacovid19vaccination |