Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner Syndrome

A 38-year-old woman with a history of recurrent deep venous thromboses (DVTs) on chronic anticoagulation presented with acute left leg swelling. The patient was diagnosed with an acute left lower extremity (LLE) DVT in the setting of May-Thurner syndrome for which treatment with unfractionated hepar...

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Main Authors: Yekaterina Kim, Daniel C. Choi, Ali N. Zaidi
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2017/8530476
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author Yekaterina Kim
Daniel C. Choi
Ali N. Zaidi
author_facet Yekaterina Kim
Daniel C. Choi
Ali N. Zaidi
author_sort Yekaterina Kim
collection DOAJ
description A 38-year-old woman with a history of recurrent deep venous thromboses (DVTs) on chronic anticoagulation presented with acute left leg swelling. The patient was diagnosed with an acute left lower extremity (LLE) DVT in the setting of May-Thurner syndrome for which treatment with unfractionated heparin was started. Her hospital course was complicated by a new diagnosis of heparin-induced thrombocytopenia (HIT), with an incidental discovery of a large tricuspid valve mobile mass on a transthoracic echocardiogram (TTE). Subsequent imaging confirmed multiple right atrial thrombi along with LLE venous stent thrombosis and a new right LE acute DVT. Anticoagulation with argatroban for HIT thrombosis was started. She underwent a right atrial percutaneous thrombectomy and bilateral lower extremity thrombectomy with directed angioplasty and stent placement. This presentation is a rare manifestation of HIT with extensive intracardiac and deep venous thrombi, with successful staged interventions.
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spelling doaj-art-2ec8966d51704e5396d8325a9b7f41cf2025-02-03T06:42:23ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/85304768530476Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner SyndromeYekaterina Kim0Daniel C. Choi1Ali N. Zaidi2Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USAMontefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USAMontefiore Heart & Vascular Care Center, Albert Einstein College of Medicine, Bronx, NY, USAA 38-year-old woman with a history of recurrent deep venous thromboses (DVTs) on chronic anticoagulation presented with acute left leg swelling. The patient was diagnosed with an acute left lower extremity (LLE) DVT in the setting of May-Thurner syndrome for which treatment with unfractionated heparin was started. Her hospital course was complicated by a new diagnosis of heparin-induced thrombocytopenia (HIT), with an incidental discovery of a large tricuspid valve mobile mass on a transthoracic echocardiogram (TTE). Subsequent imaging confirmed multiple right atrial thrombi along with LLE venous stent thrombosis and a new right LE acute DVT. Anticoagulation with argatroban for HIT thrombosis was started. She underwent a right atrial percutaneous thrombectomy and bilateral lower extremity thrombectomy with directed angioplasty and stent placement. This presentation is a rare manifestation of HIT with extensive intracardiac and deep venous thrombi, with successful staged interventions.http://dx.doi.org/10.1155/2017/8530476
spellingShingle Yekaterina Kim
Daniel C. Choi
Ali N. Zaidi
Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner Syndrome
Case Reports in Hematology
title Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner Syndrome
title_full Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner Syndrome
title_fullStr Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner Syndrome
title_full_unstemmed Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner Syndrome
title_short Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner Syndrome
title_sort extensive intracardiac and deep venous thromboses in a young woman with heparin induced thrombocytopenia and may thurner syndrome
url http://dx.doi.org/10.1155/2017/8530476
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AT danielcchoi extensiveintracardiacanddeepvenousthrombosesinayoungwomanwithheparininducedthrombocytopeniaandmaythurnersyndrome
AT alinzaidi extensiveintracardiacanddeepvenousthrombosesinayoungwomanwithheparininducedthrombocytopeniaandmaythurnersyndrome