Systemic heparin administration impairs lung development in neonatal mice

Systemic heparin administration impairs lung development in neonatal mice

Abstract Preterm infants born in the saccular stage of lung development are at risk for developing bronchopulmonary dysplasia (BPD). Oxygen toxicity and volutrauma are identified as major contributors of BPD. Despite mitigation of these risks preterm infants continue to be affected by chronic lung d...

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Main Authors: Thomas I. Hirsch, Savas T. Tsikis, Scott C. Fligor, Amy Shei Pan, Sarah Z. Wang, Mikayla Quigley, Srujan Dadi, Hiroko Kishikawa, Paul D. Mitchell, Colin Niaudet, Diane R. Bielenberg, Mark Puder
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-99831-x
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