Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells
Background: In our previous study we found that rhsIL-6R, along with recombinant human interleukin-6, plays a regulatory role in the immune response by modulating the tumour necrosis factor-α (TNF-α) expression and its production by peripheral blood mononuclearcells (PBMC). We also suggested that sI...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2003-01-01
|
| Series: | Mediators of Inflammation |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09629350310001633397 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832561208341823488 |
|---|---|
| author | E. Jablonskaca W. Puzewska M. Marcinczyk J. Jablonski |
| author_facet | E. Jablonskaca W. Puzewska M. Marcinczyk J. Jablonski |
| author_sort | E. Jablonskaca |
| collection | DOAJ |
| description | Background: In our previous study we found that rhsIL-6R, along with recombinant human interleukin-6, plays a regulatory role in the immune response by modulating the tumour necrosis factor-α (TNF-α) expression and its production by peripheral blood mononuclearcells (PBMC). We also suggested that sIL-6R with IL-6 secreted by human PMN (neutrophils) influenced the TNF-α expression and its production by autologous PBMC. |
| format | Article |
| id | doaj-art-2ec1e6bc7465424593d104c1f430aebd |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2003-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-2ec1e6bc7465424593d104c1f430aebd2025-02-03T01:25:36ZengWileyMediators of Inflammation0962-93511466-18612003-01-0112635535910.1080/09629350310001633397Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cellsE. Jablonskaca0W. Puzewska1M. Marcinczyk2J. Jablonski3Department of Immunology, Medical University of Bialystok, Waszyngtona 15A, Bialystok 15-274, PolandDepartment of Immunology, Medical University of Bialystok, Waszyngtona 15A, Bialystok 15-274, PolandDepartment of Immunology, Medical University of Bialystok, Waszyngtona 15A, Bialystok 15-274, PolandDepartment of Toxicology, Medical University of Bialystok, Waszyngtona 15A, Bialystok 15-274, PolandBackground: In our previous study we found that rhsIL-6R, along with recombinant human interleukin-6, plays a regulatory role in the immune response by modulating the tumour necrosis factor-α (TNF-α) expression and its production by peripheral blood mononuclearcells (PBMC). We also suggested that sIL-6R with IL-6 secreted by human PMN (neutrophils) influenced the TNF-α expression and its production by autologous PBMC.http://dx.doi.org/10.1080/09629350310001633397Soluble gp130Tumour necrosis factor-αNeutrophilsPeripheral blood mononuclear cells. |
| spellingShingle | E. Jablonskaca W. Puzewska M. Marcinczyk J. Jablonski Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells Mediators of Inflammation Soluble gp130 Tumour necrosis factor-α Neutrophils Peripheral blood mononuclear cells. |
| title | Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells |
| title_full | Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells |
| title_fullStr | Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells |
| title_full_unstemmed | Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells |
| title_short | Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells |
| title_sort | role of soluble gp130 in the tumour necrosis factor α expression and its production by peripheral blood mononuclear cells |
| topic | Soluble gp130 Tumour necrosis factor-α Neutrophils Peripheral blood mononuclear cells. |
| url | http://dx.doi.org/10.1080/09629350310001633397 |
| work_keys_str_mv | AT ejablonskaca roleofsolublegp130inthetumournecrosisfactoraexpressionanditsproductionbyperipheralbloodmononuclearcells AT wpuzewska roleofsolublegp130inthetumournecrosisfactoraexpressionanditsproductionbyperipheralbloodmononuclearcells AT mmarcinczyk roleofsolublegp130inthetumournecrosisfactoraexpressionanditsproductionbyperipheralbloodmononuclearcells AT jjablonski roleofsolublegp130inthetumournecrosisfactoraexpressionanditsproductionbyperipheralbloodmononuclearcells |