Comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide-treated counterparts
Abstract Fermentation produces diverse consumables like bread, wine, beer, and cheese, with fungi playing a key role. This study sequenced fungal and bacteria DNA from 46 commercial wines, paired by vineyard proximity, harvest time, and grape variety. One in each pair was natural, while the other ha...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-88655-4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850198051425091584 |
|---|---|
| author | Robin Mesnage Jérôme Douzelet Gilles-Eric Seralini |
| author_facet | Robin Mesnage Jérôme Douzelet Gilles-Eric Seralini |
| author_sort | Robin Mesnage |
| collection | DOAJ |
| description | Abstract Fermentation produces diverse consumables like bread, wine, beer, and cheese, with fungi playing a key role. This study sequenced fungal and bacteria DNA from 46 commercial wines, paired by vineyard proximity, harvest time, and grape variety. One in each pair was natural, while the other had pesticide treatments and microbial adjunctions. Bacteria profiles were studied using targeted sequencing of the V3-V4 region of the 16 S rRNA gene while fungal profiles were studied with ITS gene targeted sequencing. Significant variability was observed in the microbial content of these wines. We identified 19 unique fungal species in natural wines, absent in pesticide-treated ones. Some have known health roles. The most abundant was Penicillium jiangxiense in Lot-et-Garonne, known for its antitumor properties. Hyphopichia pseudoburtonii, with notable aromatic properties, was also detected, commonly found in insect and fish microbiota. Antrodia favescens, related to the medicinal Antrodia cinnamomea, was identified in another location, known for its role in Chinese herbal medicine against cancer and metabolic diseases. Ochrocladosporium elatum, recognized for its antioxidant and antibacterial activities, was found elsewhere. Additionally, natural wines exhibited greater bacterial biodiversity, contributing to unique tastes and potential health benefits. |
| format | Article |
| id | doaj-art-2ebd109056f2473582c20fe853be0fcc |
| institution | OA Journals |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-2ebd109056f2473582c20fe853be0fcc2025-08-20T02:12:58ZengNature PortfolioScientific Reports2045-23222025-02-0115111510.1038/s41598-025-88655-4Comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide-treated counterpartsRobin Mesnage0Jérôme DouzeletGilles-Eric Seralini1Buchinger Wilhelmi ClinicNetwork on Risks, Quality and Sustainable Environment, Department of Biology, Esplanade de la Paix, University of Caen NormandyAbstract Fermentation produces diverse consumables like bread, wine, beer, and cheese, with fungi playing a key role. This study sequenced fungal and bacteria DNA from 46 commercial wines, paired by vineyard proximity, harvest time, and grape variety. One in each pair was natural, while the other had pesticide treatments and microbial adjunctions. Bacteria profiles were studied using targeted sequencing of the V3-V4 region of the 16 S rRNA gene while fungal profiles were studied with ITS gene targeted sequencing. Significant variability was observed in the microbial content of these wines. We identified 19 unique fungal species in natural wines, absent in pesticide-treated ones. Some have known health roles. The most abundant was Penicillium jiangxiense in Lot-et-Garonne, known for its antitumor properties. Hyphopichia pseudoburtonii, with notable aromatic properties, was also detected, commonly found in insect and fish microbiota. Antrodia favescens, related to the medicinal Antrodia cinnamomea, was identified in another location, known for its role in Chinese herbal medicine against cancer and metabolic diseases. Ochrocladosporium elatum, recognized for its antioxidant and antibacterial activities, was found elsewhere. Additionally, natural wines exhibited greater bacterial biodiversity, contributing to unique tastes and potential health benefits.https://doi.org/10.1038/s41598-025-88655-4 |
| spellingShingle | Robin Mesnage Jérôme Douzelet Gilles-Eric Seralini Comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide-treated counterparts Scientific Reports |
| title | Comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide-treated counterparts |
| title_full | Comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide-treated counterparts |
| title_fullStr | Comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide-treated counterparts |
| title_full_unstemmed | Comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide-treated counterparts |
| title_short | Comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide-treated counterparts |
| title_sort | comparative analysis of fungal and bacterial composition in natural wines and their closest pesticide treated counterparts |
| url | https://doi.org/10.1038/s41598-025-88655-4 |
| work_keys_str_mv | AT robinmesnage comparativeanalysisoffungalandbacterialcompositioninnaturalwinesandtheirclosestpesticidetreatedcounterparts AT jeromedouzelet comparativeanalysisoffungalandbacterialcompositioninnaturalwinesandtheirclosestpesticidetreatedcounterparts AT gillesericseralini comparativeanalysisoffungalandbacterialcompositioninnaturalwinesandtheirclosestpesticidetreatedcounterparts |