Differences in sensory nerve block between levobupivacaine and bupivacaine at low concentrations in humans and animals.

Physiochemical properties of levobupivacaine and bupivacaine are identical, but pharmacokinetic and pharmacodynamics properties differ due to stereoselective interactions at the molecular sites of action. An evaluation of nerve block characteristics is essential for optimal clinical application. Thi...

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Bibliographic Details
Main Authors: Akiyuki Sakamoto, Satoshi Tanaka, Takashi Ishida, Mikito Kawamata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0306591
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