Associations between Ozone and Emphysema: A Systematic Review and Meta-analysis
Abstract Air pollution is widely viewed as a serious threat to human health and a contributor to deaths. Air pollution appears to be linked to the progression of emphysema, according to epidemiological data. The objective of this study was to examine associations between air pollution and the progre...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2022-05-01
|
| Series: | Aerosol and Air Quality Research |
| Subjects: | |
| Online Access: | https://doi.org/10.4209/aaqr.220027 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825197583154282496 |
|---|---|
| author | Amja Manullang Yueh-Lun Lee Vincent Laiman Jer-Hwa Chang Hsiao-Chi Chuang |
| author_facet | Amja Manullang Yueh-Lun Lee Vincent Laiman Jer-Hwa Chang Hsiao-Chi Chuang |
| author_sort | Amja Manullang |
| collection | DOAJ |
| description | Abstract Air pollution is widely viewed as a serious threat to human health and a contributor to deaths. Air pollution appears to be linked to the progression of emphysema, according to epidemiological data. The objective of this study was to examine associations between air pollution and the progression of emphysema using a meta-analysis. A meta-analysis was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) protocol. A systematic literature search was conducted using the Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medline, Embase, PubMed, and Web of Science bibliographic databases. A random-effects model for the meta-analysis was implemented to summarize effect estimates of sufficiently comparable outcomes and pollutants (e.g.: particulate matter, nitrogen oxides and ozone), and the results were visualized in forest plots. We observed that a 1-ppb rise in O3 was associated with a 0.30 increase in the percent emphysema progression (95% CI: 0.02, 0.57, p < 0.05). In contrast, no significant association was found between PM2.5 or NO2 exposure and the percent change in emphysema. Increasing O3 concentrations may have an impact on and exacerbate human health conditions such as emphysema and respiratory diseases. Air quality and climate change should be concerns for future environmental policies and protection measures. |
| format | Article |
| id | doaj-art-2eb2b97c5ea44476ae4ca870b42da47b |
| institution | Kabale University |
| issn | 1680-8584 2071-1409 |
| language | English |
| publishDate | 2022-05-01 |
| publisher | Springer |
| record_format | Article |
| series | Aerosol and Air Quality Research |
| spelling | doaj-art-2eb2b97c5ea44476ae4ca870b42da47b2025-02-09T12:17:18ZengSpringerAerosol and Air Quality Research1680-85842071-14092022-05-012261910.4209/aaqr.220027Associations between Ozone and Emphysema: A Systematic Review and Meta-analysisAmja Manullang0Yueh-Lun Lee1Vincent Laiman2Jer-Hwa Chang3Hsiao-Chi Chuang4International Ph.D. Program in Medicine, College of Medicine, Taipei Medical UniversityDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical UniversityInternational Ph.D. Program in Medicine, College of Medicine, Taipei Medical UniversitySchool of Respiratory Therapy, College of Medicine, Taipei Medical UniversitySchool of Respiratory Therapy, College of Medicine, Taipei Medical UniversityAbstract Air pollution is widely viewed as a serious threat to human health and a contributor to deaths. Air pollution appears to be linked to the progression of emphysema, according to epidemiological data. The objective of this study was to examine associations between air pollution and the progression of emphysema using a meta-analysis. A meta-analysis was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) protocol. A systematic literature search was conducted using the Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medline, Embase, PubMed, and Web of Science bibliographic databases. A random-effects model for the meta-analysis was implemented to summarize effect estimates of sufficiently comparable outcomes and pollutants (e.g.: particulate matter, nitrogen oxides and ozone), and the results were visualized in forest plots. We observed that a 1-ppb rise in O3 was associated with a 0.30 increase in the percent emphysema progression (95% CI: 0.02, 0.57, p < 0.05). In contrast, no significant association was found between PM2.5 or NO2 exposure and the percent change in emphysema. Increasing O3 concentrations may have an impact on and exacerbate human health conditions such as emphysema and respiratory diseases. Air quality and climate change should be concerns for future environmental policies and protection measures.https://doi.org/10.4209/aaqr.220027Air pollutionCOPDEmphysemaMeta-analysisOzone |
| spellingShingle | Amja Manullang Yueh-Lun Lee Vincent Laiman Jer-Hwa Chang Hsiao-Chi Chuang Associations between Ozone and Emphysema: A Systematic Review and Meta-analysis Aerosol and Air Quality Research Air pollution COPD Emphysema Meta-analysis Ozone |
| title | Associations between Ozone and Emphysema: A Systematic Review and Meta-analysis |
| title_full | Associations between Ozone and Emphysema: A Systematic Review and Meta-analysis |
| title_fullStr | Associations between Ozone and Emphysema: A Systematic Review and Meta-analysis |
| title_full_unstemmed | Associations between Ozone and Emphysema: A Systematic Review and Meta-analysis |
| title_short | Associations between Ozone and Emphysema: A Systematic Review and Meta-analysis |
| title_sort | associations between ozone and emphysema a systematic review and meta analysis |
| topic | Air pollution COPD Emphysema Meta-analysis Ozone |
| url | https://doi.org/10.4209/aaqr.220027 |
| work_keys_str_mv | AT amjamanullang associationsbetweenozoneandemphysemaasystematicreviewandmetaanalysis AT yuehlunlee associationsbetweenozoneandemphysemaasystematicreviewandmetaanalysis AT vincentlaiman associationsbetweenozoneandemphysemaasystematicreviewandmetaanalysis AT jerhwachang associationsbetweenozoneandemphysemaasystematicreviewandmetaanalysis AT hsiaochichuang associationsbetweenozoneandemphysemaasystematicreviewandmetaanalysis |