Adipose-derived stem cells attenuate rheumatoid arthritis by restoring CX3CR1+ synovial lining macrophage barrier

Adipose-derived stem cells attenuate rheumatoid arthritis by restoring CX3CR1+ synovial lining macrophage barrier

Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune disease and the integrity of CX3CR1+ synovial macrophage barrier significantly impacts its progression. However, the mechanisms driving the dynamic changes of this macrophage barrier remain unclear. Traditional drug therapies for...

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Bibliographic Details
Main Authors:	Lei Wang, Ming Hao, Yongyue Xu, Zhaoyan Wang, Hanqi Xie, Bo Zhang, Xue Zhang, Jun Lin, Xiaodan Sun, Jianbin Wang, Qiong Wu
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Series:	Stem Cell Research & Therapy
Subjects:	Mesenchymal stem cells Rheumatoid arthritis Macrophage Mitochondria
Online Access:	https://doi.org/10.1186/s13287-025-04144-5
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