Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias Surgery
Background: Parenteral testosterone has been used to increase glans diameter and penis size before hypospadias surgery. However, the existing literature data are scarce in the Indian context. Aim: The present study aimed to assess the efficacy of parenteral testosterone injection on diameter at the...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-05-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1628_24 |
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| author | Praveen S. Baghel Anil Dawar Roshan Mandloi Sarika Rawat Sonu Rawat |
| author_facet | Praveen S. Baghel Anil Dawar Roshan Mandloi Sarika Rawat Sonu Rawat |
| author_sort | Praveen S. Baghel |
| collection | DOAJ |
| description | Background:
Parenteral testosterone has been used to increase glans diameter and penis size before hypospadias surgery. However, the existing literature data are scarce in the Indian context.
Aim:
The present study aimed to assess the efficacy of parenteral testosterone injection on diameter at the base of the penis, glans diameter, and penile length before surgery.
Methods:
The study assessed 40 hypospadia subjects who were given testosterone propionate injection a 2 mg/kg body weight dose given deep intramuscularly in three doses at 3-week gap before reconstructive surgery. Before surgery, diameter at the base of the penis, glans diameter, and penile length was assessed.
Results:
The study results showed a mean increase in diameter at the base of the penis, glans diameter, and penile length after parenteral testosterone therapy as 0.94 ± 0.14, 1.03 ± 0.48, and 1.09 ± 0.25, respectively. All three factors were statistically significant with P < 0.001.
Conclusion:
Intramuscular testosterone injection leads to an increase in diameter at the base of the penis, glans diameter, and penile length without any notable associated severe side effects. However, minor side effects are associated, including aggressiveness, acne, and fine pubic hair development. |
| format | Article |
| id | doaj-art-2e8808d07b2340ed80fea00a0d6adb48 |
| institution | OA Journals |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-2e8808d07b2340ed80fea00a0d6adb482025-08-20T02:03:24ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-05-0117Suppl 1S742S74410.4103/jpbs.jpbs_1628_24Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias SurgeryPraveen S. BaghelAnil DawarRoshan MandloiSarika RawatSonu RawatBackground: Parenteral testosterone has been used to increase glans diameter and penis size before hypospadias surgery. However, the existing literature data are scarce in the Indian context. Aim: The present study aimed to assess the efficacy of parenteral testosterone injection on diameter at the base of the penis, glans diameter, and penile length before surgery. Methods: The study assessed 40 hypospadia subjects who were given testosterone propionate injection a 2 mg/kg body weight dose given deep intramuscularly in three doses at 3-week gap before reconstructive surgery. Before surgery, diameter at the base of the penis, glans diameter, and penile length was assessed. Results: The study results showed a mean increase in diameter at the base of the penis, glans diameter, and penile length after parenteral testosterone therapy as 0.94 ± 0.14, 1.03 ± 0.48, and 1.09 ± 0.25, respectively. All three factors were statistically significant with P < 0.001. Conclusion: Intramuscular testosterone injection leads to an increase in diameter at the base of the penis, glans diameter, and penile length without any notable associated severe side effects. However, minor side effects are associated, including aggressiveness, acne, and fine pubic hair development.https://journals.lww.com/10.4103/jpbs.jpbs_1628_24glans diameterglans penishypospadiaspenile lengthtestosterone |
| spellingShingle | Praveen S. Baghel Anil Dawar Roshan Mandloi Sarika Rawat Sonu Rawat Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias Surgery Journal of Pharmacy and Bioallied Sciences glans diameter glans penis hypospadias penile length testosterone |
| title | Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias Surgery |
| title_full | Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias Surgery |
| title_fullStr | Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias Surgery |
| title_full_unstemmed | Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias Surgery |
| title_short | Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias Surgery |
| title_sort | assessing the efficacy of parental testosterone therapy in the penis size before hypospadias surgery |
| topic | glans diameter glans penis hypospadias penile length testosterone |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_1628_24 |
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