Aminooxyacetic acid ameliorates alcohol-induced learning and memory deficits through BDNF-TrkB pathway and calcium homeostasis

Abstract Chronic alcohol-related brain damage (ARBD) is mainly manifested as learning and memory impairment and cognitive decline in the long term. Ca2+ plays a key role in learning and memory impairment. The increase of intracellular Ca2+ concentration can directly cause mitochondrial dysfunction,...

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Bibliographic Details
Main Authors: Zhen Sun, Meinan Nie, Xunling Wang, Bolin Jiao, Jiayi Fu, Ailin Du
Format: Article
Language:English
Published: BMC 2025-05-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02630-3
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