Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease

Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease

ObjectiveTo identify key cerebrospinal fluid (CSF) metabolomic biomarkers associated with Parkinson’s disease (PD) and prodromal PD, providing insights for intervention strategy development.MethodsSix hundred and thirty-nine participants from the Parkinson’s Progression Markers Initiative (PPMI) coh...

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Bibliographic Details
Main Authors: Yifan Zhang, Yuexin Yan, Xiangxu Kong, Haijun Zhang, Shengyuan Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson diseases
metabolomic biomarkers
early prediction model
bidirectional Mendelian randomization
PD susceptibility
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1582362/full
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