Arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatment

Introduction: Tuberculosis (TB) is considered one of the two greater long-term global public health threats than the coronavirus disease 2019 (COVID-19) pandemic. Although venous thromboembolism has a low prevalence of 3.5% among patients with active TB, miliary TB complicated by arteriovenous thro...

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Main Authors: Ling Chen, Quanxian Liu, Yuanbo Lan, Hong Zhang
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2023-09-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/17744
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author Ling Chen
Quanxian Liu
Yuanbo Lan
Hong Zhang
author_facet Ling Chen
Quanxian Liu
Yuanbo Lan
Hong Zhang
author_sort Ling Chen
collection DOAJ
description Introduction: Tuberculosis (TB) is considered one of the two greater long-term global public health threats than the coronavirus disease 2019 (COVID-19) pandemic. Although venous thromboembolism has a low prevalence of 3.5% among patients with active TB, miliary TB complicated by arteriovenous thrombosis is a rare and potentially life-threatening condition. Case study: We present here an unusual case of a 32-year-old man with a two-month history of shortness of breath and painful swelling in the right lower extremity. In addition, elevated plasma levels of platelets, white blood cells, neutrophils, and D-dimer were observed upon his admission to the hospital. The patient was diagnosed with miliary TB complicated by arteriovenous thrombosis in the right lower extremity and a left ventricular mass measuring 3.5 × 1.7 cm. He was successfully treated with anti-TB drugs and low molecular weight heparin followed by warfarin, aspirin and clopidogrel. Conclusions: This case study demonstrates that a patient with miliary TB complicated by arteriovenous thrombosis and a left ventricular mass can be cured with timely diagnosis and appropriate treatment. The implications of this report are to raise awareness about miliary TB and arteriovenous thrombosis, to improve diagnosis and treatment, and to reduce patient mortality through sharing our successful experience with clinicians and healthcare providers in the developing countries of the world.
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publisher The Journal of Infection in Developing Countries
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spelling doaj-art-2e79f230692f4533804a69b42de9d8eb2025-08-20T02:27:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-09-01170910.3855/jidc.17744Arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatmentLing Chen0Quanxian Liu1Yuanbo Lan2Hong Zhang3Department of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaZ-BioMed, Inc., Rockville, Maryland, United States Introduction: Tuberculosis (TB) is considered one of the two greater long-term global public health threats than the coronavirus disease 2019 (COVID-19) pandemic. Although venous thromboembolism has a low prevalence of 3.5% among patients with active TB, miliary TB complicated by arteriovenous thrombosis is a rare and potentially life-threatening condition. Case study: We present here an unusual case of a 32-year-old man with a two-month history of shortness of breath and painful swelling in the right lower extremity. In addition, elevated plasma levels of platelets, white blood cells, neutrophils, and D-dimer were observed upon his admission to the hospital. The patient was diagnosed with miliary TB complicated by arteriovenous thrombosis in the right lower extremity and a left ventricular mass measuring 3.5 × 1.7 cm. He was successfully treated with anti-TB drugs and low molecular weight heparin followed by warfarin, aspirin and clopidogrel. Conclusions: This case study demonstrates that a patient with miliary TB complicated by arteriovenous thrombosis and a left ventricular mass can be cured with timely diagnosis and appropriate treatment. The implications of this report are to raise awareness about miliary TB and arteriovenous thrombosis, to improve diagnosis and treatment, and to reduce patient mortality through sharing our successful experience with clinicians and healthcare providers in the developing countries of the world. https://jidc.org/index.php/journal/article/view/17744Miliary tuberculosisarteriovenous thrombosisbiomarkertreatment
spellingShingle Ling Chen
Quanxian Liu
Yuanbo Lan
Hong Zhang
Arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatment
Journal of Infection in Developing Countries
Miliary tuberculosis
arteriovenous thrombosis
biomarker
treatment
title Arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatment
title_full Arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatment
title_fullStr Arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatment
title_full_unstemmed Arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatment
title_short Arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatment
title_sort arteriovenous thrombosis in a patient with miliary tuberculosis complicated by a left ventricular mass and its treatment
topic Miliary tuberculosis
arteriovenous thrombosis
biomarker
treatment
url https://jidc.org/index.php/journal/article/view/17744
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AT quanxianliu arteriovenousthrombosisinapatientwithmiliarytuberculosiscomplicatedbyaleftventricularmassanditstreatment
AT yuanbolan arteriovenousthrombosisinapatientwithmiliarytuberculosiscomplicatedbyaleftventricularmassanditstreatment
AT hongzhang arteriovenousthrombosisinapatientwithmiliarytuberculosiscomplicatedbyaleftventricularmassanditstreatment