Therapeutic applications of botulinum neurotoxins in head and neck disorders
Objective: The aim of this article is to review the mechanism of action, physiological effects, and therapeutic applications of botulinum neurotoxins in the head and neck area. Study design: An extensive literature search was performed using keywords. The resulting articles were analyzed for relevan...
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| Format: | Article |
| Language: | English |
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Springer
2015-01-01
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| Series: | Saudi Dental Journal |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1013905214000807 |
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| _version_ | 1849699773656858624 |
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| author | Ahmad Alshadwi Mohammed Nadershah Timothy Osborn |
| author_facet | Ahmad Alshadwi Mohammed Nadershah Timothy Osborn |
| author_sort | Ahmad Alshadwi |
| collection | DOAJ |
| description | Objective: The aim of this article is to review the mechanism of action, physiological effects, and therapeutic applications of botulinum neurotoxins in the head and neck area. Study design: An extensive literature search was performed using keywords. The resulting articles were analyzed for relevance in four areas: overview on botulinum neurotoxins, the role of botulinum neurotoxins in the management of salivary secretory disorders, the role of botulinum neurotoxins in the management of facial pain, and the role of botulinum neurotoxins in head and neck movement disorders. Institutional review board approval was not needed due the nature of the study. Results: Botulinum neurotoxin therapy was demonstrated to be a valuable alternative to conventional medical therapy for many conditions affecting the head and neck area in terms of morbidly, mortality, and patient satisfaction with treatment outcomes. Conclusion: Botulinum neurotoxin therapy provides viable alternatives to traditional treatment modalities for some conditions affecting the head and neck region that have neurological components. This therapy can overcome some of the morbidities associated with conventional therapy. More research is needed to determine the ideal doses of botulinum neurotoxin to treat different diseases affecting the head and neck regions. Keywords: Botulinum toxin, Botox, Temporomandibular disorder, Dystonia, Facial pain |
| format | Article |
| id | doaj-art-2e753fd3ea3c46a3bd3d59b1b7e1a3da |
| institution | DOAJ |
| issn | 1013-9052 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Springer |
| record_format | Article |
| series | Saudi Dental Journal |
| spelling | doaj-art-2e753fd3ea3c46a3bd3d59b1b7e1a3da2025-08-20T03:18:28ZengSpringerSaudi Dental Journal1013-90522015-01-0127131110.1016/j.sdentj.2014.10.001Therapeutic applications of botulinum neurotoxins in head and neck disordersAhmad Alshadwi0Mohammed Nadershah1Timothy Osborn2Department of Oral and Maxillofacial Surgery, Boston University-Henry M. Goldman School of Dental Medicine, 100 East Newton Street, Suite G-407, Boston, MA 02118, United States; King Feisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia; Corresponding author at: Department of Oral and Maxillofacial Surgery, Boston University, Boston Medical Center, 100 East Newton street, Boston, MA 02118, United States. Tel.: +1 617 414 4838; fax: +1 617 414 4126.Academic Faculty King Abdulaziz University-Dental School, Jeddah, Saudi ArabiaDepartment of Oral and Maxillofacial Surgery, Boston University-Henry M. Goldman School of Dental Medicine, 100 East Newton Street, Suite G-407, Boston, MA 02118, United StatesObjective: The aim of this article is to review the mechanism of action, physiological effects, and therapeutic applications of botulinum neurotoxins in the head and neck area. Study design: An extensive literature search was performed using keywords. The resulting articles were analyzed for relevance in four areas: overview on botulinum neurotoxins, the role of botulinum neurotoxins in the management of salivary secretory disorders, the role of botulinum neurotoxins in the management of facial pain, and the role of botulinum neurotoxins in head and neck movement disorders. Institutional review board approval was not needed due the nature of the study. Results: Botulinum neurotoxin therapy was demonstrated to be a valuable alternative to conventional medical therapy for many conditions affecting the head and neck area in terms of morbidly, mortality, and patient satisfaction with treatment outcomes. Conclusion: Botulinum neurotoxin therapy provides viable alternatives to traditional treatment modalities for some conditions affecting the head and neck region that have neurological components. This therapy can overcome some of the morbidities associated with conventional therapy. More research is needed to determine the ideal doses of botulinum neurotoxin to treat different diseases affecting the head and neck regions. Keywords: Botulinum toxin, Botox, Temporomandibular disorder, Dystonia, Facial painhttp://www.sciencedirect.com/science/article/pii/S1013905214000807 |
| spellingShingle | Ahmad Alshadwi Mohammed Nadershah Timothy Osborn Therapeutic applications of botulinum neurotoxins in head and neck disorders Saudi Dental Journal |
| title | Therapeutic applications of botulinum neurotoxins in head and neck disorders |
| title_full | Therapeutic applications of botulinum neurotoxins in head and neck disorders |
| title_fullStr | Therapeutic applications of botulinum neurotoxins in head and neck disorders |
| title_full_unstemmed | Therapeutic applications of botulinum neurotoxins in head and neck disorders |
| title_short | Therapeutic applications of botulinum neurotoxins in head and neck disorders |
| title_sort | therapeutic applications of botulinum neurotoxins in head and neck disorders |
| url | http://www.sciencedirect.com/science/article/pii/S1013905214000807 |
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