Emerging role of the cGAS-STING pathway in cardiovascular diseases: biologic function, mechanisms and targeted therapy
Abstract Currently, cardiovascular diseases (CVDs) represent a substantial threat to human health and wellness. Accumulating evidence has increasingly highlighted the pivotal role of the DNA-activated cyclic GMP-AMP (cGAMP) synthase (cGAS)-stimulator of interferon gene (STING) pathway in the progres...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s10020-025-01273-8 |
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