Similarities between bacterial GAD and human GAD65: Implications in gut mediated autoimmune type 1 diabetes.

Similarities between bacterial GAD and human GAD65: Implications in gut mediated autoimmune type 1 diabetes.

A variety of islet autoantibodies (AAbs) can predict and possibly dictate eventual type 1 diabetes (T1D) diagnosis. Upwards of 75% of those with T1D are positive for AAbs against glutamic acid decarboxylase (GAD65 or GAD), a producer of gamma-aminobutyric acid (GABA) in human pancreatic beta cells....

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Main Authors: Suhana Bedi, Tiffany M Richardson, Baofeng Jia, Hadeel Saab, Fiona S L Brinkman, Monica Westley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261103&type=printable
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